2. Gene
  3. MLXIP - MLX interacting protein Gene

MLXIP - MLX interacting protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as MIR; MONDOA; bHLHe36

Gene ID: 22877 | Gene type: protein coding

About MLXIP

Cytogenetic location: 12q24.31 Genomic coordinates (GRCh38): 12:122,078,756-122,147,344 (from NCBI)

This gene has 11 transcripts (splice variants), 1 gene allele, 203 orthologues and 3 paralogues. Ubiquitous expression in colon (RPKM 27.3), ovary (RPKM 19.2) and 25 other tissues.

Summary

This gene encodes a protein that functions as part of a heterodimer to activate transcription. The encoded protein forms a heterodimer with Max-like protein X (MLX) and is involved in the regulation of genes in response to cellular glucose levels. [provided by RefSeq, Mar 2014]

MLXIP Products(1)

mRNA Protein Name
NM_014938.6 NP_055753.3 MLX-interacting protein
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
11073985 GOA
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
11073985 GOA
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11073985 GOA
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
16782875 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MLXIP Protein Structure

HLH

HLH: Helix-loop-helix DNA-binding domain (721 - 770)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 919 a.a.
Protein Preferred Names Protein Names

MLX-interacting protein

Mlx interactor

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08504 MLXIP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MLXIP MGD MGI:2141183
Canis familiaris MLXIP VGNC VGNC:43268
Rattus norvegicus MLXIP RGD RGD:1560774
Macaca mulatta MLXIP VGNC VGNC:74785
Felis catus MLXIP VGNC VGNC:63529
Bos taurus MLXIP VGNC VGNC:31509