2. Gene
  3. MAST3 - microtubule associated serine/threonine kinase 3 Gene

MAST3 - microtubule associated serine/threonine kinase 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DEE108

Gene ID: 23031 | Gene type: protein coding

About MAST3

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:18,097,778-18,151,687 (from NCBI)

This gene has 10 transcripts (splice variants), 273 orthologues and 13 paralogues. Broad expression in brain (RPKM 16.8), spleen (RPKM 6.6) and 24 other tissues.

Summary

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in Cytoskeleton organization; intracellular signal transduction; and peptidyl-serine phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]

MAST3 Products(22)

mRNA Protein Name
NM_001393501.1 NP_001380430.1 microtubule-associated serine/threonine-protein kinase 3 isoform 1
NM_001393502.1 NP_001380431.1 microtubule-associated serine/threonine-protein kinase 3 isoform 2
NM_001393503.1 NP_001380432.1 microtubule-associated serine/threonine-protein kinase 3 isoform 3
NM_001393504.1 NP_001380433.1 microtubule-associated serine/threonine-protein kinase 3 isoform 4
NM_001393505.1 NP_001380434.1 microtubule-associated serine/threonine-protein kinase 3 isoform 5
NM_001393506.1 NP_001380435.1 microtubule-associated serine/threonine-protein kinase 3 isoform 6
NM_001393507.1 NP_001380436.1 microtubule-associated serine/threonine-protein kinase 3 isoform 7
NM_001393508.1 NP_001380437.1 microtubule-associated serine/threonine-protein kinase 3 isoform 8
NM_001393509.1 NP_001380438.1 microtubule-associated serine/threonine-protein kinase 3 isoform 9
NM_001393510.1 NP_001380439.1 microtubule-associated serine/threonine-protein kinase 3 isoform 10
NM_001393511.1 NP_001380440.1 microtubule-associated serine/threonine-protein kinase 3 isoform 11
NM_001393512.1 NP_001380441.1 microtubule-associated serine/threonine-protein kinase 3 isoform 12
NM_001393513.1 NP_001380442.1 microtubule-associated serine/threonine-protein kinase 3 isoform 13
NM_001393514.1 NP_001380443.1 microtubule-associated serine/threonine-protein kinase 3 isoform 14
NM_001393515.1 NP_001380444.1 microtubule-associated serine/threonine-protein kinase 3 isoform 15
NM_001393516.1 NP_001380445.1 microtubule-associated serine/threonine-protein kinase 3 isoform 16
NM_001393517.1 NP_001380446.1 microtubule-associated serine/threonine-protein kinase 3 isoform 17
NM_001393518.1 NP_001380447.1 microtubule-associated serine/threonine-protein kinase 3 isoform 18
NM_001393519.1 NP_001380448.1 microtubule-associated serine/threonine-protein kinase 3 isoform 19
NM_001393520.1 NP_001380449.1 microtubule-associated serine/threonine-protein kinase 3 isoform 21
NM_001393521.1 NP_001380450.1 microtubule-associated serine/threonine-protein kinase 3 isoform 22
NM_015016.2 NP_055831.1 microtubule-associated serine/threonine-protein kinase 3 isoform 20

MAST3 Protein Structure

DUF1908

DUF1908: Domain of unknown function (DUF1908) (58 - 332)

Pkinase

Pkinase: Protein kinase domain (367 - 640)

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (976 - 1032)

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  • 1309 a.a.
Protein Preferred Names Protein Names

microtubule-associated serine/threonine-protein kinase 3

Related Diseases

Diseases Alias
Inflammatory Bowel Disease 6

IBD6
Mega-Corpus-Callosum Syndrome With Cerebellar Hypoplasia And Cortical Malformations

MCCCHCM
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08163 MAST3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris MAST3 VGNC VGNC:43034
Mus musculus MAST3 MGD MGI:2683541
Rattus norvegicus MAST3 RGD RGD:1587639
Bos taurus MAST3 VGNC VGNC:31259
Felis catus MAST3 VGNC VGNC:63394
Macaca mulatta MAST3 VGNC VGNC:74533