2. Gene
  3. ZZEF1 - zinc finger ZZ-type and EF-hand domain containing 1 Gene

ZZEF1 - zinc finger ZZ-type and EF-hand domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as ZZZ4

Gene ID: 23140 | Gene type: protein coding

About ZZEF1

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:4,004,445-4,143,030 (from NCBI)

This gene has 11 transcripts (splice variants) and 189 orthologues. Ubiquitous expression in small intestine (RPKM 12.0), colon (RPKM 10.1) and 25 other tissues.

Summary

Predicted to enable ubiquitin-like protein Ligase activity. Predicted to act upstream of or within several processes, including glutamatergic synaptic transmission; regulation of peptidyl-tyrosine phosphorylation; and visual learning. Predicted to be located in cell surface; postsynapse; and presynaptic active zone. [provided by Alliance of Genome Resources, Apr 2022]

ZZEF1 Products(1)

mRNA Protein Name
NM_015113.4 NP_055928.3 zinc finger ZZ-type and EF-hand domain-containing protein 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables histone reader activity IMP
IMP: Inferred from mutant phenotype
33227311 GOA
enables lysine-acetylated histone binding IDA
IDA: Inferred from direct assay
33227311 GOA
enables methylated histone binding IDA
IDA: Inferred from direct assay
33227311 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
33227311 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZZEF1 Protein Structure

ANAPC10

ANAPC10: Anaphase-promoting complex, subunit 10 (APC10) (263 - 378)

ZZ

ZZ: Zinc finger, ZZ type (1781 - 1819)

ZZ

ZZ: Zinc finger, ZZ type (1828 - 1868)

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  • 2961 a.a.
Protein Preferred Names Protein Names

zinc finger ZZ-type and EF-hand domain-containing protein 1

zinc finger, ZZ-type with EF hand domain 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16216 ZZEF1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ZZEF1 VGNC VGNC:37396
Canis familiaris ZZEF1 VGNC VGNC:48870
Macaca mulatta ZZEF1 VGNC VGNC:79769
Rattus norvegicus ZZEF1 RGD RGD:1311189
Mus musculus ZZEF1 MGD MGI:2444286
Felis catus ZZEF1 VGNC VGNC:67395