DNAJC9 - DnaJ heat shock protein family (Hsp40) member C9 Gene

Homo sapiens

Also known as JDD1; SB73; HDJC9

Gene ID: 23234 | Gene type: protein coding

About DNAJC9

Cytogenetic location: 10q22.2 Genomic coordinates (GRCh38): 10:73,232,272-73,247,255 (from NCBI)

This gene has 3 transcripts (splice variants), 206 orthologues and 20 paralogues. Ubiquitous expression in bone marrow (RPKM 34.5), lymph node (RPKM 15.2) and 24 other tissues.

Summary

Enables chaperone binding activity; heat shock protein binding activity; and histone binding activity. Involved in nucleosome assembly and positive regulation of ATPase activity. Located in several cellular components, including cytosol; extracellular space; and nucleoplasm. Part of chaperone complex. [provided by Alliance of Genome Resources, Apr 2022]

DNAJC9 Products(1)

mRNA	Protein	Name
NM_015190.5	NP_056005.1	dnaJ homolog subfamily C member 9

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables heat shock protein binding	IPI IPI: Inferred from physical interaction	17182002	GOA
enables histone binding	IDA IDA: Inferred from direct assay	33857403	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	19410544	GOA
enables protein-folding chaperone binding	IDA IDA: Inferred from direct assay	33857403	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in nucleosome assembly	IDA IDA: Inferred from direct assay	33857403	GOA
involved in positive regulation of ATP-dependent activity	IDA IDA: Inferred from direct assay	17182002	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	17182002	GOA
located in extracellular space	IDA IDA: Inferred from direct assay	17182002	GOA
located in nucleus	IDA IDA: Inferred from direct assay	17182002	GOA
located in plasma membrane	IDA IDA: Inferred from direct assay	17182002	GOA
part of protein folding chaperone complex	IDA IDA: Inferred from direct assay	33857403	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DNAJC9 Protein Structure

DnaJ

0
100
200
260 a.a.

Protein Preferred Names

Protein Names

dnaJ homolog subfamily C member 9

DnaJ (Hsp40) homolog, subfamily C, member 9

Related Diseases

Diseases

Alias

Epithelial Recurrent Erosion Dystrophy

ERED	Corneal Erosions, Recurring Hereditary
Col17a1	Dystrophia Helsinglandica
Dystrophia Smolandiensis	Recurrent Hereditary Corneal Erosions
Rces	Recurrent Corneal Erosion Syndrome
Recurrent Erosion Of Cornea

Recurrent Corneal Erosion

Recurrent Erosion Of Cornea	Recurrent Erosion Syndrome
Corneal Erosion	Non-Traumatic Recurrent Erosion Of Cornea

Epithelial And Subepithelial Dystrophy

Verrucous Carcinoma

Verrucous Squamous Carcinoma	Verrucous Squamous Cell Carcinoma
Warty Carcinoma	Carcinoma Verrucous
Carcinoma, Verrucous

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03890	DNAJC9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	DNAJC9	VGNC	VGNC:55985
Mus musculus	DNAJC9	MGD	MGI:1915326
Rattus norvegicus	DNAJC9	RGD	RGD:1305009
Others	DNAJC9	NCBI

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