2. Gene
  3. USP24 - ubiquitin specific peptidase 24 Gene

USP24 - ubiquitin specific peptidase 24 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 23358 | Gene type: protein coding

About USP24

Cytogenetic location: 1p32.3 Genomic coordinates (GRCh38): 1:55,066,359-55,215,364 (from NCBI)

This gene has 7 transcripts (splice variants), 164 orthologues and 71 paralogues. Ubiquitous expression in bone marrow (RPKM 9.9), lymph node (RPKM 9.7) and 25 other tissues.

Summary

Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating Enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating Enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008]

USP24 Products(1)

mRNA Protein Name
NM_015306.3 NP_056121.2 ubiquitin carboxyl-terminal hydrolase 24

USP24 Protein Structure

UCH

UCH: Ubiquitin carboxyl-terminal hydrolase (1689 - 2039)

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  • 2620 a.a.
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 24

deubiquitinating enzyme 24

Related Diseases

Diseases Alias
Non-Syndromic X-Linked Intellectual Disability 99

Mrx99

X-Linked Mental Retardation 99
Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease
Fanconi Anemia, Complementation Group A

Fanconi Anemia

Fanconi Pancytopenia

Fanconi Anemia Complementation Group A

FANCA

Fa

Fanconi Panmyelopathy

Fanconi'S Anemia

Fanconi Anaemia

Fanconi'S Anaemia

Fanconi Hypoplastic Anemia

Estren-Dameshek Variant Of Fanconi Anemia

Estren-Dameshek Variant Of Fanconi Pancytopenia

Fanconi Anemia Estren-Dameshek Variant

Fanconis Anemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-111408 EOAI3402143 Inhibitor 98.95% Unkown
HY-RS15534 USP24 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta USP24 VGNC VGNC:78743
Rattus norvegicus USP24 RGD RGD:1306799
Felis catus USP24 VGNC VGNC:66874
Mus musculus USP24 MGD MGI:1919936
Bos taurus USP24 VGNC VGNC:36717
Canis familiaris USP24 VGNC VGNC:48183