2. Gene
  3. BICRAL - BICRA like chromatin remodeling complex associated protein Gene

BICRAL - BICRA like chromatin remodeling complex associated protein Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SMARCK2; GLTSCR1L; KIAA0240

Gene ID: 23506 | Gene type: protein coding

About BICRAL

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:42,746,339-42,868,556 (from NCBI)

This gene has 3 transcripts (splice variants), 203 orthologues and 1 paralogue. Ubiquitous expression in ovary (RPKM 8.6), thyroid (RPKM 7.9) and 25 other tissues.

Summary

Predicted to be involved in positive regulation of transcription, DNA-templated. Part of SWI/SNF complex. [provided by Alliance of Genome Resources, Apr 2022]

BICRAL Products(3)

mRNA Protein Name
NM_001318819.2 NP_001305748.1 BRD4-interacting chromatin-remodeling complex-associated protein-like
NM_001393499.1 NP_001380428.1 BRD4-interacting chromatin-remodeling complex-associated protein-like
NM_015349.3 NP_056164.1 BRD4-interacting chromatin-remodeling complex-associated protein-like
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Cellular Component GO Annotation Evidence Reference Source
part of SWI/SNF complex IDA
IDA: Inferred from direct assay
29374058 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BICRAL Protein Structure

GLTSCR1

GLTSCR1: Conserved region of unknown function on GLTSCR protein (704 - 807)

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  • 1079 a.a.
Protein Preferred Names Protein Names

BRD4-interacting chromatin-remodeling complex-associated protein-like

BRD4 interacting chromatin remodeling complex associated protein like

BICRAL Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra BICRAL Q6AI39 ARHGDIG Homo sapiens Q99819
Validated Y2H
32296183
Intra BICRAL Q6AI39 BANP Homo sapiens Q8N9N5-2
Validated Y2H
32296183
Intra BICRAL Q6AI39 NGLY1 Homo sapiens Q96IV0
Validated Y2H
32296183
Intra BICRAL Q6AI39 USHBP1 Homo sapiens Q8N6Y0
Validated Y2H
32296183
Intra BICRAL Q6AI39 DTX2 Homo sapiens Q86UW9
Validated Y2H
32296183
Intra BICRAL Q6AI39 EXOC8 Homo sapiens Q8IYI6
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Clear Cell Adenofibroma

Cystadenofibroma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01501 BICRAL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus BICRAL MGD MGI:2673855
Canis familiaris BICRAL VGNC VGNC:38455
Rattus norvegicus BICRAL RGD RGD:1305680
Bos taurus BICRAL VGNC VGNC:26495
Felis catus BICRAL VGNC VGNC:60114
Macaca mulatta BICRAL VGNC VGNC:70359