2. Gene
  3. CHST5 - carbohydrate sulfotransferase 5 Gene

CHST5 - carbohydrate sulfotransferase 5 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as gn6st-3; hIGn6ST; I-GlcNAc6ST; glcNAc6ST-3; I-GlcNAc-6-ST

Gene ID: 23563 | Gene type: protein coding

About CHST5

Cytogenetic location: 16q23.1 Genomic coordinates (GRCh38): 16:75,528,530-75,536,108 (from NCBI)

This gene has 2 transcripts (splice variants), 71 orthologues and 6 paralogues. Biased expression in colon (RPKM 16.2), duodenum (RPKM 16.2) and 2 other tissues.

Summary

The protein encoded by this gene belongs to the Gal/GalNAc/GlcNAc 6-O-sulfotransferase (GST) family, members of which catalyze the transfer of sulfate to position 6 of galactose (Gal), N-acetylgalactosamine (GalNAc), or N-acetylglucosamine (GlcNAc) residues within proteoglycans, and sulfation of O-linked sugars of mucin-type acceptors. Carbohydrate sulfation plays a critical role in many biologic processes. This gene is predominantly expressed in colon and small intestine. [provided by RefSeq, Aug 2011]

CHST5 Products(1)

mRNA Protein Name
NM_024533.5 NP_078809.2 carbohydrate sulfotransferase 5
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables N-acetylglucosamine 6-O-sulfotransferase activity IDA
IDA: Inferred from direct assay
10491328 GOA
Biological Process GO Annotation Evidence Reference Source
involved in N-acetylglucosamine metabolic process IDA
IDA: Inferred from direct assay
10491328 GOA
involved in sulfur compound metabolic process IDA
IDA: Inferred from direct assay
10491328 GOA
Cellular Component GO Annotation Evidence Reference Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
12855678 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CHST5 Protein Structure

Sulfotransfer_1

Sulfotransfer_1: Sulfotransferase domain (64 - 378)

  • 0
  • 100
  • 200
  • 300
  • 411 a.a.
Protein Preferred Names Protein Names

carbohydrate sulfotransferase 5

GST4-alpha

Related Diseases

Diseases Alias
Macular Dystrophy, Corneal

Macular Corneal Dystrophy

MCD

Corneal Dystrophy, Macular Type

Groenouw Type Ii Corneal Dystrophy

Fehr Corneal Dystrophy

Macular Dystrophy, Corneal Type 1

Mcdc1

Macular Corneal Dystrophy Type Ii

Macular Corneal Dystrophy, Type Ii

Macular Corneal Dystrophy, Type I

Mcdc1, Formerly

Macular Dystrophy, Corneal, 1

Macular Corneal Dystrophy Type 1

Corneal Dystrophy Groenouw Type Ii

Corneal Dystrophy Macular Type

Macular Corneal Dystrophy Type I

Dystrophy, Macular, Corneal
Corneal Dystrophy, Groenouw Type I

CDGG1

Gcd1

Groenouw Corneal Dystrophy Type I

Granular Corneal Dystrophy 1

Granular Corneal Dystrophy Type I

Corneal Dystrophy Groenouw Type I

Granular Corneal Dystrophy, Type I

Corneal Dystrophy, Punctate Or Nodular

Groenouw Type I Corneal Dystrophy

Corneal Dystrophy Granular Type

Corneal Dystrophy Punctate Or Nodular

Classic Gcd

Classic Granular Corneal Dystrophy

Gcdi

Granular Corneal Dystrophy Type 1

Corneal Dystrophy, Groenouw Type 1

Mesh

D003317

Punctate Or Nodular Corneal Dystrophy

Dystrophy, Corneal, Groenouw Type I
Ehlers-Danlos Syndrome, Spondylodysplastic Type, 1

Xylosylprotein 4-Beta-Galactosyltransferase Deficiency

Xgpt Deficiency

EDSSPD1

Ehlers-Danlos Syndrome With Short Stature And Limb Anomalies

Edssla

Proteodermatan Sulfate, Defective Biosynthesis Of

Pds, Defective Biosynthesis Of

Dermatan Sulfate Proteoglycan

Galactosyltransferase I Deficiency

Ehlers-Danlos Syndrome Spondylodysplastic Type 1

Spondylodysplastic Ehlers-Danlos Syndrome

Ehlers-Danlos Syndrome, Progeroid Type, 1, Formerly

Edsp1, Formerly

Ehlers-Danlos Syndrome, Progeroid Type

Galactosyltransferase 1 Deficiency

Spondylodysplastic Eds

Speds

Defective Biosynthesis Of Pds

Defective Biosynthesis Of Proteodermatan Sulfate

Edsp1

Ehlers-Danlos Syndrome, Progeroid Type, 1

Proteodermatan Sulfate Defective Biosynthesis Of

Ehlers-Danlos, Spondylodysplastic Syndrome

Ehlers-Danlos Syndrome, Progeroid Form
Joubert Syndrome 20

JBTS20

Joubert Syndrome, Type 20
Blepharochalasis

Dermatolysis Palpebrarum

Adiposa Ptosis
Stromal Dystrophy
Corneal Dystrophy, Lisch Epithelial

Lisch Epithelial Corneal Dystrophy

LECD

Band-Shaped And Whorled Microcystic Corneal Epithelial Dystrophy

Band-Shaped And Whorled Microcystic

Band-Shaped And Whorled Microcystic Dystrophy Of The Corneal Epithelium
Spondyloepiphyseal Dysplasia, Kimberley Type

SEDK

Spondyloepiphyseal Dysplasia Kimberley Type

Spondyloepiphyseal Dysplasia Type Kimberley

Dysplasia, Spondyloepiphyseal, Kimberley Type
Granular Corneal Dystrophy

Granular Dystrophy Corneal

Corneal Dystrophies, Hereditary

Hereditary Corneal Dystrophy

Corneal Dystrophy Nos

Familial Hereditary Corneal Degeneration

Hereditary Corneal Opacity
Sorsby Fundus Dystrophy

SFD

Fundus Dystrophy, Pseudoinflammatory, Of Sorsby

Sorsby'S Fundus Dystrophy

Macular Dystrophy, Hemorrhagic

Hemorrhagic Macular Dystrophy

Pseudoinflammatory Fundus Dystrophy Of Sorsby

Sorsby'S Pseudoinflammatory Macular Dystrophy

Sorsby Pseudoinflammatory Fundus Dystrophy

Dystrophy, Fundus, Sorsby
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02691 CHST5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CHST5 MGD MGI:1931825
Others CHST5 NCBI