CHST5 - carbohydrate sulfotransferase 5 Gene

Homo sapiens

Also known as gn6st-3; hIGn6ST; I-GlcNAc6ST; glcNAc6ST-3; I-GlcNAc-6-ST

Gene ID: 23563 | Gene type: protein coding

About CHST5

Cytogenetic location: 16q23.1 Genomic coordinates (GRCh38): 16:75,528,530-75,536,108 (from NCBI)

This gene has 2 transcripts (splice variants), 71 orthologues and 6 paralogues. Biased expression in colon (RPKM 16.2), duodenum (RPKM 16.2) and 2 other tissues.

Summary

The protein encoded by this gene belongs to the Gal/GalNAc/GlcNAc 6-O-sulfotransferase (GST) family, members of which catalyze the transfer of sulfate to position 6 of galactose (Gal), N-acetylgalactosamine (GalNAc), or N-acetylglucosamine (GlcNAc) residues within proteoglycans, and sulfation of O-linked sugars of mucin-type acceptors. Carbohydrate sulfation plays a critical role in many biologic processes. This gene is predominantly expressed in colon and small intestine. [provided by RefSeq, Aug 2011]

CHST5 Products(1)

mRNA	Protein	Name
NM_024533.5	NP_078809.2	carbohydrate sulfotransferase 5

CHST5 Protein Structure

Sulfotransfer_1

0
100
200
300
411 a.a.

Protein Preferred Names

Protein Names

carbohydrate sulfotransferase 5

GST4-alpha

Related Diseases

Diseases

Alias

Macular Dystrophy, Corneal

Macular Corneal Dystrophy	MCD
Corneal Dystrophy, Macular Type	Groenouw Type Ii Corneal Dystrophy
Fehr Corneal Dystrophy	Macular Dystrophy, Corneal Type 1
Mcdc1	Macular Corneal Dystrophy Type Ii
Macular Corneal Dystrophy, Type Ii	Macular Corneal Dystrophy, Type I
Mcdc1, Formerly	Macular Dystrophy, Corneal, 1
Macular Corneal Dystrophy Type 1	Corneal Dystrophy Groenouw Type Ii
Corneal Dystrophy Macular Type	Macular Corneal Dystrophy Type I
Dystrophy, Macular, Corneal

Corneal Dystrophy, Groenouw Type I

CDGG1	Gcd1
Groenouw Corneal Dystrophy Type I	Granular Corneal Dystrophy 1
Granular Corneal Dystrophy Type I	Corneal Dystrophy Groenouw Type I
Granular Corneal Dystrophy, Type I	Corneal Dystrophy, Punctate Or Nodular
Groenouw Type I Corneal Dystrophy	Corneal Dystrophy Granular Type
Corneal Dystrophy Punctate Or Nodular	Classic Gcd
Classic Granular Corneal Dystrophy	Gcdi
Granular Corneal Dystrophy Type 1	Corneal Dystrophy, Groenouw Type 1
Mesh	D003317
Punctate Or Nodular Corneal Dystrophy	Dystrophy, Corneal, Groenouw Type I

Ehlers-Danlos Syndrome, Spondylodysplastic Type, 1

Xylosylprotein 4-Beta-Galactosyltransferase Deficiency	Xgpt Deficiency
EDSSPD1	Ehlers-Danlos Syndrome With Short Stature And Limb Anomalies
Edssla	Proteodermatan Sulfate, Defective Biosynthesis Of
Pds, Defective Biosynthesis Of	Dermatan Sulfate Proteoglycan
Galactosyltransferase I Deficiency	Ehlers-Danlos Syndrome Spondylodysplastic Type 1
Spondylodysplastic Ehlers-Danlos Syndrome	Ehlers-Danlos Syndrome, Progeroid Type, 1, Formerly
Edsp1, Formerly	Ehlers-Danlos Syndrome, Progeroid Type
Galactosyltransferase 1 Deficiency	Spondylodysplastic Eds
Speds	Defective Biosynthesis Of Pds
Defective Biosynthesis Of Proteodermatan Sulfate	Edsp1
Ehlers-Danlos Syndrome, Progeroid Type, 1	Proteodermatan Sulfate Defective Biosynthesis Of
Ehlers-Danlos, Spondylodysplastic Syndrome	Ehlers-Danlos Syndrome, Progeroid Form

Joubert Syndrome 20

JBTS20

Joubert Syndrome, Type 20

Blepharochalasis

Dermatolysis Palpebrarum

Adiposa Ptosis

Stromal Dystrophy

Corneal Dystrophy, Lisch Epithelial

Lisch Epithelial Corneal Dystrophy	LECD
Band-Shaped And Whorled Microcystic Corneal Epithelial Dystrophy	Band-Shaped And Whorled Microcystic
Band-Shaped And Whorled Microcystic Dystrophy Of The Corneal Epithelium

Spondyloepiphyseal Dysplasia, Kimberley Type

SEDK	Spondyloepiphyseal Dysplasia Kimberley Type
Spondyloepiphyseal Dysplasia Type Kimberley	Dysplasia, Spondyloepiphyseal, Kimberley Type

Granular Corneal Dystrophy

Granular Dystrophy Corneal	Corneal Dystrophies, Hereditary
Hereditary Corneal Dystrophy	Corneal Dystrophy Nos
Familial Hereditary Corneal Degeneration	Hereditary Corneal Opacity

Sorsby Fundus Dystrophy

SFD	Fundus Dystrophy, Pseudoinflammatory, Of Sorsby
Sorsby'S Fundus Dystrophy	Macular Dystrophy, Hemorrhagic
Hemorrhagic Macular Dystrophy	Pseudoinflammatory Fundus Dystrophy Of Sorsby
Sorsby'S Pseudoinflammatory Macular Dystrophy	Sorsby Pseudoinflammatory Fundus Dystrophy
Dystrophy, Fundus, Sorsby

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02691	CHST5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CHST5	MGD	MGI:1931825
Others	CHST5	NCBI

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