2. Gene
  3. Clec5a - C-type lectin domain family 5, member a Gene

Clec5a - C-type lectin domain family 5, member a Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Mdl1; Ly100; MDL-1; Clecsf5

Gene ID: 23845 | Gene type: protein coding

About Clec5a

Summary

Enables virus receptor activity. Involved in several processes, including innate immune response; negative regulation of apoptotic process; and osteoblast development. Acts upstream of or within myeloid cell differentiation and negative regulation of myeloid cell apoptotic process. Located in cell surface. Orthologous to human CLEC5A (C-type lectin domain containing 5A). [provided by Alliance of Genome Resources, Apr 2022]

Clec5a Products(2)

mRNA Protein Name
NM_001038604.1 NP_001033693.1 C-type lectin domain family 5 member A isoform 1
NM_021364.2 NP_067339.1 C-type lectin domain family 5 member A isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19074552 MGI
enables virus receptor activity IDA
IDA: Inferred from direct assay
18496526 MGI
Biological Process GO Annotation Evidence Reference Source
involved in innate immune response IDA
IDA: Inferred from direct assay
19074552 MGI
acts upstream of or within myeloid cell differentiation IGI
IGI: Inferred from genetic interaction
24216483 MGI
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
19074552 MGI
acts upstream of or within negative regulation of myeloid cell apoptotic process IDA
IDA: Inferred from direct assay
19074552 MGI
involved in osteoblast development IDA
IDA: Inferred from direct assay
19251634 MGI
involved in positive regulation of cytokine production IMP
IMP: Inferred from mutant phenotype
18496526 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
19074552 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-type lectin domain family 5 member A

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5

C-type lectin superfamily member 5

myeloid DAP12-associating lectin 1

type II transmembrane protein MDL-1

Clec5a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Clec5a Q9R007 Tyrobp Mus musculus O54885
Anti Bait CoIP
19251634
Intra
Clec5a Q9R007 Hcst Mus musculus Q9QUJ0
Anti Bait CoIP
19251634
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Clec5a Proteins

Cat. No. Product Name Accession Purity
HY-P77906 CLEC5A/MDL-1 Protein, Mouse (HEK293, Fc) Q9R007-3 (Y26-K190) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02798 CLEC5A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clec5a NCBI NCBI:23601
Rattus norvegicus Clec5a NCBI NCBI:679787
Macaca mulatta Clec5a NCBI NCBI:695425