2. Gene
  3. LAMP5 - lysosomal associated membrane protein family member 5 Gene

LAMP5 - lysosomal associated membrane protein family member 5 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as LAMP-5; UNC-46; BADLAMP; BAD-LAMP; C20orf103

Gene ID: 24141 | Gene type: protein coding

About LAMP5

Cytogenetic location: 20p12.2 Genomic coordinates (GRCh38): 20:9,514,590-9,530,524 (from NCBI)

This gene has 2 transcripts (splice variants), 200 orthologues and 3 paralogues. Biased expression in brain (RPKM 17.1), ovary (RPKM 10.7) and 6 other tissues.

Summary

Predicted to be involved in establishment of protein localization to organelle. Located in endoplasmic reticulum-Golgi intermediate compartment membrane; endosome membrane; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

LAMP5 Products(2)

mRNA Protein Name
NM_001199897.2 NP_001186826.1 lysosome-associated membrane glycoprotein 5 isoform 2 precursor
NM_012261.4 NP_036393.1 lysosome-associated membrane glycoprotein 5 isoform 1 precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in endoplasmic reticulum-Golgi intermediate compartment membrane IDA
IDA: Inferred from direct assay
21642595 GOA
located in endosome membrane IDA
IDA: Inferred from direct assay
21642595 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
21642595 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LAMP5 Protein Structure

Lamp

Lamp: Lysosome-associated membrane glycoprotein (Lamp) (42 - 263)

  • 0
  • 100
  • 200
  • 280 a.a.
Protein Preferred Names Protein Names

lysosome-associated membrane glycoprotein 5

LAMP family protein C20orf103

Recombinant LAMP5 Proteins

Cat. No. Product Name Accession Purity
HY-P77978 LAMP5/BAD-LAMP Protein, Human (HEK293, Fc) Q9UJQ1-1 (E30-E235) ≥95%
HY-P700775 LAMP5/BAD-LAMP Protein, Human (HEK293, His) Q9UJQ1-1 (E30-E235) ≥95%

Related Diseases

Diseases Alias
Epilepsy, Familial Temporal Lobe, 5

Familial Temporal Lobe Epilepsy 5

ETL5

Epilepsy, Temporal Lobe, Familial, Type 5
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07512 LAMP5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus LAMP5 RGD RGD:1306991
Mus musculus LAMP5 MGD MGI:1923411
Canis familiaris LAMP5 VGNC VGNC:42576
Bos taurus LAMP5 VGNC VGNC:30778
Felis catus LAMP5 VGNC VGNC:63188
Macaca mulatta LAMP5 VGNC VGNC:74055
Macaca fascicularis LAMP5 NCBI NCBI:102137452
Others LAMP5 NCBI