2. Gene
  3. C4A - C4a complement C4A Gene

C4A - C4a complement C4A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as C4; C4b; C4-1

Gene ID: 24233 | Gene type: protein coding

About C4A

Summary

Predicted to enable complement component C1q complex binding activity. Predicted to be involved in complement activation and positive regulation of apoptotic cell clearance. Located in extracellular space. Human ortholog(s) of this gene implicated in autistic disorder; autoimmune disease (multiple); complement deficiency (multiple); and renal cell carcinoma. Orthologous to several human genes including C4B (complement C4B (Chido blood group)). [provided by Alliance of Genome Resources, Apr 2022]

C4A Products(1)

mRNA Protein Name
NM_031504.3 NP_113692.2 complement C4 precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in extracellular region IDA
IDA: Inferred from direct assay
8805663 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
15634920 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

complement C4

complement C4-like

complement component 4 (within H-2S)

complement component 4, gene 1

complement component 4A (Rodgers blood group)

complement component 4B (Chido blood group)

complement component 4B (Childo blood group)

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01745 C4A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W324243 11β-HSD1-IN-9 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens C4A NCBI NCBI:720
Mus musculus C4A NCBI NCBI:625018