2. Gene
  3. Cryaa - crystallin, alpha A Gene

Cryaa - crystallin, alpha A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Crya1; Acry-1

Gene ID: 24273 | Gene type: protein coding

About Cryaa

Summary

This gene encodes subunit a, one of two subunits of alpha-crystallin, which is a high molecular weight, soluble aggregate and is a member of the small heat shock protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. It acts as a molecular chaperone and is the major protein in the eye lens, maintaining the transparency and refractive index of the lens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Cryaa Products(2)

mRNA Protein Name
NM_001289737.1 NP_001276666.1 alpha-crystallin A chain isoform 2
NM_012534.4 NP_036666.2 alpha-crystallin A chain isoform 1
Protein Preferred Names Protein Names

alpha-crystallin A chain

Crystallin, alpha polypeptide A

Cryaa Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Cryaa P24623 CRYGD Homo sapiens P07320
Fluorescence
22289178
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03206 CRYAA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cryaa NCBI NCBI:1409