2. Gene
  3. Gp6 - glycoprotein 6 (platelet) Gene

Gp6 - glycoprotein 6 (platelet) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gpvi; Gm469; 9830166G18Rik

Gene ID: 243816 | Gene type: protein coding

About Gp6

Summary

Enables collagen binding activity and collagen receptor activity. Involved in vasculature development. Acts upstream of or within collagen-activated tyrosine kinase receptor signaling pathway. Is integral component of plasma membrane. Is expressed in bone marrow; femur; liver; and spleen. Human ortholog(s) of this gene implicated in platelet-type bleeding disorder 11. Orthologous to human GP6 (Glycoprotein VI platelet). [provided by Alliance of Genome Resources, Apr 2022]

Gp6 Products(1)

mRNA Protein Name
NM_001163014.1 NP_001156486.1 platelet glycoprotein VI precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables collagen binding IDA
IDA: Inferred from direct assay
10961879 MGI
enables collagen receptor activity IMP
IMP: Inferred from mutant phenotype
27609517 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within collagen-activated signaling pathway IMP
IMP: Inferred from mutant phenotype
27609517 MGI
acts upstream of or within collagen-activated tyrosine kinase receptor signaling pathway IDA
IDA: Inferred from direct assay
28032533 MGI
acts upstream of or within collagen-activated tyrosine kinase receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
27609517 MGI
acts upstream of or within peptidyl-tyrosine phosphorylation IDA
IDA: Inferred from direct assay
28032533 MGI
acts upstream of or within platelet aggregation IDA
IDA: Inferred from direct assay
28032533 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
28032533 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10961879 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet glycoprotein VI

glycoprotein 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05611 GP6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gp6 NCBI NCBI:51206
Macaca fascicularis Gp6 NCBI NCBI:102118698
Macaca mulatta Gp6 NCBI NCBI:100424512