1. Gene
  2. Il6r - interleukin 6 receptor Gene

Il6r - interleukin 6 receptor Gene

Rattus norvegicus

Also known as IL6R1; Il6ra

Gene ID: 24499 | Gene type: protein coding

About Il6r

Summary

Predicted to enable several functions, including cytokine binding activity; cytokine receptor activity; and protein homodimerization activity. Predicted to contribute to ciliary neurotrophic factor receptor activity and interleukin-6 receptor binding activity. Involved in several processes, including response to cAMP; response to gamma radiation; and response to lipopolysaccharide. Located in extracellular space and neuronal cell body membrane. Biomarker of several diseases, including congestive heart failure; mental depression; orchitis; sciatic neuropathy; and visual epilepsy. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; hyper IgE syndrome; obesity; and stomach Cancer. Orthologous to human IL6R (interleukin 6 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Il6r Products(1)

mRNA Protein Name
NM_017020.3 NP_058716.2 interleukin-6 receptor subunit alpha precursor
Protein Preferred Names Protein Names

interleukin-6 receptor subunit alpha

IL-6 receptor subunit alpha

IL-6R 1

IL-6R subunit alpha

IL-6R-alpha

IL-6RA

interleukin 6 receptor, alpha

Recombinant Il6r Proteins

Cat. No. Product Name Accession Purity
HY-P73224 IL-6R Protein, Rat (HEK293, His) NP_058716.2 (L20-P364) ≥95%
HY-P73876 IL-6R Protein, Rat (HEK293, Fc) NP_058716.2 (L20-P364) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens Il6r NCBI NCBI:3570
Mus musculus Il6r NCBI