2. Gene
  3. Npr1 - natriuretic peptide receptor 1 Gene

Npr1 - natriuretic peptide receptor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Gca; Npra; Anpra; NPR-A

Gene ID: 24603 | Gene type: protein coding

About Npr1

Summary

Enables Guanylate Cyclase activity. Involved in several processes, including cGMP-mediated signaling; negative regulation of smooth muscle cell proliferation; and positive regulation of cGMP-mediated signaling. Located in plasma membrane. Used to study hypertension. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human NPR1 (natriuretic peptide receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Npr1 Products(1)

mRNA Protein Name
NM_012613.1 NP_036745.1 atrial natriuretic peptide receptor 1 precursor
Protein Preferred Names Protein Names

atrial natriuretic peptide receptor 1

ANP-A

ANPR-A

GC-A

atrial natriuretic peptide A-type receptor

atrial natriuretic peptide receptor A

atrial natriuretic peptide receptor type A

guanylate cyclase A

natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1419 AP 811 Antagonist 98.07% Unkown
HY-153650 JS11 Inhibitor 99.22% Unkown
HY-P1419A AP 811 acetate Antagonist / Unkown
HY-RS09497 NPR1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990921 Imelciment / Unkown
HY-P990951 Vixticibart / Unkown
HY-P991121 Baloncibart Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Npr1 NCBI NCBI:4881
Macaca fascicularis Npr1 NCBI NCBI:102143449
Mus musculus Npr1 NCBI NCBI:18160