2. Gene
  3. Gnal - G protein subunit alpha L Gene

Gnal - G protein subunit alpha L Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Olf; Golf; RGD1305940

Gene ID: 24611 | Gene type: protein coding

About Gnal

Summary

Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in cellular response to dopamine and regulation of long-term synaptic depression. Predicted to be part of heterotrimeric G-protein complex. Used to study dystonia. Human ortholog(s) of this gene implicated in dystonia 25. Orthologous to human GNAL (G protein subunit alpha L). [provided by Alliance of Genome Resources, Apr 2022]

Gnal Products(1)

mRNA Protein Name
NM_001191836.2 NP_001178765.1 guanine nucleotide-binding protein G(olf) subunit alpha
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to dopamine IMP
IMP: Inferred from mutant phenotype
31678405 RGD
involved in regulation of long-term synaptic depression IMP
IMP: Inferred from mutant phenotype
31678405 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide-binding protein G(olf) subunit alpha

Olf-alpha protein (olfactory neuron-specific G protein)

adenylate cyclase-stimulating G alpha protein, olfactory type

guanine nucleotide binding protein, alpha activating activity polypeptide, olfactory type

guanine nucleotide binding protein, alpha st

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05537 GNAL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gnal NCBI NCBI:2774
Macaca fascicularis Gnal NCBI NCBI:102137826
Mus musculus Gnal NCBI NCBI:14680
Macaca mulatta Gnal NCBI NCBI:114673806