2. Gene
  3. Serpina1 - serpin family A member 1 Gene

Serpina1 - serpin family A member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Pi; AAT; Spi1

Gene ID: 24648 | Gene type: protein coding

About Serpina1

Summary

Enables serine-type endopeptidase inhibitor activity. Involved in several processes, including negative regulation of serine-type endopeptidase activity; response to estradiol; and response to methanol. Located in extracellular space. Used to study pulmonary hypertension. Biomarker of asthma; osteoarthritis; pancreatitis (multiple); primary hyperaldosteronism; and proteinuria. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; chronic obstructive pulmonary disease (multiple); human immunodeficiency virus infectious disease; inflammatory bowel disease (multiple); and liver disease (multiple). Orthologous to human SERPINA1 (serpin family A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Serpina1 Products(1)

mRNA Protein Name
NM_022519.2 NP_071964.2 alpha-1-antiproteinase precursor
Protein Preferred Names Protein Names

alpha-1-antiproteinase

alpha-1-antitrypsin (protease inhibitor)

alpha-1-protease inhibitor

alpha-1-proteinase inhibitor

serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

serine (or cysteine) proteinase inhibitor, clade A, mem

Recombinant Serpina1 Proteins

Cat. No. Product Name Accession Purity
HY-P74556 Serpin A1 Protein, Rat (HEK293, His) P17475 (E25-R411) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-107098 PPL-100 free acid / Unkown
HY-RS12696 SERPINA1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Serpina1 NCBI NCBI:5265
Mus musculus Serpina1 NCBI