2. Gene
  3. Slc2a1 - solute carrier family 2 member 1 Gene

Slc2a1 - solute carrier family 2 member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as GTG1; Gtg3; GLUTB; Glut1; RATGTG1

Gene ID: 24778 | Gene type: protein coding

About Slc2a1

Primary_assembly 5: 132,717,196-132,745,416 forward strand.mRatBN7.2:CM026978.1

This gene has 3 transcripts (splice variants), 374 orthologues, 12 paralogues and is associated with 52 phenotypes. Biased expression in Brain (RPKM 185.1), Kidney (RPKM 121.2) and 9 other tissues.

Summary

Enables several functions, including D-glucose transmembrane transporter activity; dehydroascorbic acid transmembrane transporter activity; and kinase binding activity. Involved in several processes, including cellular hyperosmotic response; cellular response to mechanical stimulus; and dehydroascorbic acid transport. Located in several cellular components, including Z disc; basolateral plasma membrane; and intercalated disc. Colocalizes with sarcolemma. Biomarker of hypertension; hypothyroidism; and middle cerebral artery infarction. Human ortholog(s) of this gene implicated in brain disease (multiple); carbohydrate metabolic disorder; myelomeningocele; obesity; and type 2 diabetes mellitus. Orthologous to human SLC2A1 (solute carrier family 2 member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slc2a1 Products(1)

mRNA Protein Name
NM_138827.2 NP_620182.1 solute carrier family 2, facilitated glucose transporter member 1

Slc2a1 Protein Structure

MFS_GLUT_Class1

MFS_GLUT_Class1: cd17431 (13 - 457)

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  • 492 a.a.
Protein Preferred Names Protein Names

solute carrier family 2, facilitated glucose transporter member 1

GLUT-1

Solute carrier family 2 a 1 (facilitated glucose transporter) brain

glucose transporter type 1, erythrocyte/brain

solute carrier family 2 (facilitated glucose transporter), member 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13157 SLC2A1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13158 Slc2a1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13159 Slc2a1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc2a1 NCBI NCBI:6513