1. Gene
  2. Adk - adenosine kinase Gene

Adk - adenosine kinase Gene

Rattus norvegicus

Also known as AK

Gene ID: 25368 | Gene type: protein coding

About Adk

Primary_assembly 15: 2,863,244-3,246,510 reverse strand.mRatBN7.2:CM026988.1

This gene has 2 transcripts (splice variants), 275 orthologues, 3 paralogues and is associated with 17 phenotypes. Biased expression in Liver (RPKM 121.9), Kidney (RPKM 595.5) and 9 other tissues.

Summary

Enables Adenosine Kinase activity. Involved in several processes, including adenosine metabolic process; circadian regulation of gene expression; and type B pancreatic cell proliferation. Located in cytoplasm and nucleus. Used to study brain infarction. Biomarker of temporal lobe epilepsy. Human ortholog(s) of this gene implicated in hypermethioninemia due to Adenosine Kinase deficiency. Orthologous to human ADK (Adenosine Kinase). [provided by Alliance of Genome Resources, Apr 2022]

Adk Products(1)

mRNA Protein Name
NM_012895.3 NP_037027.2 adenosine kinase

Adk Protein Structure

ribokinase_pfkB_like

ribokinase_pfkB_like: cl00192 (69 - 401)

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  • 300
  • 403 a.a.
Protein Preferred Names Protein Names

adenosine kinase

adenosine 5'-phosphotransferase

Orthologs Information

Species Symbol Source ID
Homo sapiens Adk NCBI NCBI:132