2. Gene
  3. WDR27 - WD repeat domain 27 Gene

WDR27 - WD repeat domain 27 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 253769 | Gene type: protein coding

About WDR27

This gene has 19 transcripts (splice variants), 211 orthologues and 26 paralogues. Ubiquitous expression in testis (RPKM 1.4), ovary (RPKM 1.4) and 25 other tissues.

Summary

This gene encodes a protein with multiple WD repeats. Proteins with these repeats may form scaffolds for protein-protein interaction and play key roles in cell signalling. Alternative splicing results in multiple transcript variants, but the full-length structure of some of these variants cannot be determined. [provided by RefSeq, Nov 2015]

WDR27 Products(5)

mRNA Protein Name
NM_001202550.2 NP_001189479.1 WD repeat-containing protein 27 isoform 2
NM_001350623.2 NP_001337552.1 WD repeat-containing protein 27 isoform 3
NM_001350624.2 NP_001337553.1 WD repeat-containing protein 27 isoform 4
NM_001350625.2 NP_001337554.1 WD repeat-containing protein 27 isoform 4
NM_182552.5 NP_872358.4 WD repeat-containing protein 27 isoform 1

WDR27 Protein Structure

WD40

WD40: WD domain, G-beta repeat (188 - 223)

WD40

WD40: WD domain, G-beta repeat (579 - 613)

WD40

WD40: WD domain, G-beta repeat (821 - 838)

(847 - 883)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 895 a.a.
Protein Preferred Names Protein Names

WD repeat-containing protein 27

Related Diseases

Diseases Alias
Cranioectodermal Dysplasia 2

CED2

Sensenbrenner Syndrome 2

Dysplasia, Cranioectodermal, Type 2
Lacrimal Duct Obstruction

Blocked Lacrimal Canaliculus

Obstruction Of Lacrimal Canaliculus

Obstruction Of Lacrimal Ducts
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15771 WDR27 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus WDR27 VGNC VGNC:50073
Canis familiaris WDR27 VGNC VGNC:55017
Macaca mulatta WDR27 VGNC VGNC:81192
Felis catus WDR27 VGNC VGNC:102547
Rattus norvegicus WDR27 RGD RGD:1309633
Mus musculus WDR27 MGD MGI:1918932