2. Gene
  3. Faslg - Fas ligand Gene

Faslg - Fas ligand Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Fasl; CD95-L; Tnfsf6; Tnlg1a; Apt1Lg1

Gene ID: 25385 | Gene type: protein coding

About Faslg

Summary

Enables death receptor binding activity and tumor necrosis factor receptor binding activity. Involved in several processes, including cellular ion homeostasis; cellular response to interferon-gamma; and extrinsic apoptotic signaling pathway via death domain receptors. Located in caveola; cytoplasmic vesicle; and perinuclear region of cytoplasm. Used to study brain glioma; substance-related disorder; and type 1 diabetes mellitus. Biomarker of several diseases, including artery disease (multiple); chronic obstructive pulmonary disease; gastric ulcer; liver disease (multiple); and ulcerative colitis. Human ortholog(s) of this gene implicated in several diseases, including cholangiocarcinoma; chronic myeloid leukemia; diabetes mellitus (multiple); pancreatic Cancer (multiple); and pre-eclampsia (multiple). Orthologous to human FASLG (Fas ligand). [provided by Alliance of Genome Resources, Apr 2022]

Faslg Products(1)

mRNA Protein Name
NM_012908.1 NP_037040.1 tumor necrosis factor ligand superfamily member 6
Protein Preferred Names Protein Names

tumor necrosis factor ligand superfamily member 6

Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand)

CD95 ligand

CD95L protein

Fas antigen ligand

Fas ligand (TNF superfamily, member 6)

Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand)

Recombinant Faslg Proteins

Cat. No. Product Name Accession Purity
HY-P74156 Fas Ligand Protein, Rat (P.pastoris, His) P36940 (L104-L278) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99445 Asunercept Inhibitor 98.13% Phase 3
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04752 FASLG Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Faslg NCBI NCBI:356
Mus musculus Faslg NCBI