2. Gene
  3. Hcrtr1 - hypocretin receptor 1 Gene

Hcrtr1 - hypocretin receptor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Hctr1

Gene ID: 25593 | Gene type: protein coding

About Hcrtr1

Primary_assembly 5: 142,477,214-142,486,674 reverse strand.mRatBN7.2:CM026978.1

This gene has 1 transcript (splice variant), 94 orthologues, 16 paralogues and is associated with 2 phenotypes. Biased expression in Adrenal (RPKM 5.7), Brain (RPKM 5.) and 8 other tissues.

Summary

Enables orexin receptor activity and peptide hormone binding activity. Involved in neuropeptide signaling pathway. Predicted to be integral component of plasma membrane. Orthologous to human HCRTR1 (hypocretin receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Hcrtr1 Products(1)

mRNA Protein Name
NM_013064.2 NP_037196.1 orexin/Hypocretin receptor type 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables orexin receptor activity IDA
IDA: Inferred from direct assay
12890892 RGD
enables peptide hormone binding IDA
IDA: Inferred from direct assay
12890892 RGD
Biological Process GO Annotation Evidence Reference Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
12890892 RGD
involved in neuropeptide signaling pathway IDA
IDA: Inferred from direct assay
12697296 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Hcrtr1 Protein Structure

7tmA_OXR

7tmA_OXR: cd15208 (46 - 368)

7tmA_OXR

7tmA_OXR: cd15208 (47 - 73)

7tmA_OXR

7tmA_OXR: cd15208 (80 - 106)

7tmA_OXR

7tmA_OXR: cd15208 (118 - 148)

7tmA_OXR

7tmA_OXR: cd15208 (159 - 180)

7tmA_OXR

7tmA_OXR: cd15208 (211 - 240)

7tmA_OXR

7tmA_OXR: cd15208 (290 - 320)

7tmA_OXR

7tmA_OXR: cd15208 (336 - 361)

  • 0
  • 100
  • 200
  • 300
  • 416 a.a.
Protein Preferred Names Protein Names

orexin/Hypocretin receptor type 1

orexin receptor type 1

hypocretin (orexin) receptor 1

hypocretin receptor type 1

ox-1-R

ox1-R

ox1r

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06051 HCRTR1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06052 Hcrtr1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06053 Hcrtr1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hcrtr1 NCBI NCBI:3061