2. Gene
  3. Il2ra - interleukin 2 receptor subunit alpha Gene

Il2ra - interleukin 2 receptor subunit alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as IL2RAC

Gene ID: 25704 | Gene type: protein coding

About Il2ra

Summary

Enables interleukin-2 receptor activity. Involved in inflammatory response to antigenic stimulus; positive regulation of T cell differentiation; and positive regulation of T cell proliferation. Located in cell surface. Used to study Korean hemorrhagic fever; asthma; and diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 41; lymphopenia; multiple sclerosis; type 1 diabetes mellitus; and type 1 diabetes mellitus 10. Orthologous to human IL2RA (interleukin 2 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Il2ra Products(1)

mRNA Protein Name
NM_013163.2 NP_037295.1 interleukin-2 receptor subunit alpha precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables interleukin-2 receptor activity IPI
IPI: Inferred from physical interaction
2592769 RGD
Biological Process GO Annotation Evidence Reference Source
involved in inflammatory response to antigenic stimulus IMP
IMP: Inferred from mutant phenotype
10389888 RGD
involved in positive regulation of T cell differentiation IMP
IMP: Inferred from mutant phenotype
9352365 RGD
involved in positive regulation of T cell proliferation IMP
IMP: Inferred from mutant phenotype
9352365 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
10210776 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-2 receptor subunit alpha

IL-2 receptor alpha subunit

IL-2 receptor subunit alpha

IL-2-RA

IL-2R subunit alpha

IL2-RA

interleukin 2 receptor, alpha chain

Recombinant Il2ra Proteins

Cat. No. Product Name Accession Purity
HY-P74809 IL-2R alpha/CD25 Protein, Rat (sf9, His) P26897/NP_037295.1 (E22-Q235) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06748 IL2RA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990086 Vopikitug Inhibitor / Unkown
HY-P991000 Imneskibart Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il2ra NCBI NCBI:3559