Mc5r - melanocortin 5 receptor Gene

Rattus norvegicus

Gene ID: 25726 | Gene type: protein coding

About Mc5r

Primary_assembly 18: 61,915,188-61,920,229 forward strand.mRatBN7.2:CM026991.1

This gene has 1 transcript (splice variant), 183 orthologues, 18 paralogues and is associated with 3 phenotypes.

Summary

Enables hormone binding activity and Melanocortin Receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human MC5R (melanocortin 5 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Mc5r Products(1)

mRNA	Protein	Name
NM_013182.3	NP_037314.1	melanocortin receptor 5

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables hormone binding	IDA IDA: Inferred from direct assay	8179577	RGD
enables hormone binding	IMP IMP: Inferred from mutant phenotype	16454799	RGD
enables melanocortin receptor activity	IDA IDA: Inferred from direct assay	8179577	RGD
enables melanocortin receptor activity	IMP IMP: Inferred from mutant phenotype	16454799	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Mc5r Protein Structure

7tm_GPCRs

0
100
200
300
325 a.a.

Protein Preferred Names

Protein Names

melanocortin receptor 5

MC5-R

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P0227	SHU 9119		99.95%	Unkown
HY-P0097A	Nonapeptide-1 acetate salt	Antagonist	98.70%	Unkown
HY-P0097	Nonapeptide-1	Antagonist	99.04%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mc5r	NCBI	NCBI:4161

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