CD6 - Cd6 Cd6 molecule Gene

Rattus norvegicus

Also known as OX52

Gene ID: 25752 | Gene type: protein coding

About CD6

Summary

Enables protein kinase binding activity. Involved in positive regulation of protein phosphorylation. Is spanning component of plasma membrane. Orthologous to human CD6 (CD6 molecule). [provided by Alliance of Genome Resources, Apr 2022]

CD6 Products(1)

mRNA	Protein	Name
NM_175577.3	NP_783167.2	T-cell differentiation antigen CD6 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	12525577	RGD
enables protein kinase binding	IDA IDA: Inferred from direct assay	12525577	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of protein phosphorylation	IDA IDA: Inferred from direct assay	12525577	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell surface	IDA IDA: Inferred from direct assay	12525577	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

T-cell differentiation antigen CD6

CD6 antigen, Tp120

T-cell differentiation antigen CD6-like

Recombinant CD6 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72924	CD6 Protein, Rat (HEK293, His)	Q812A4 (L18-N396)	≥95%

Related Agents

Clinical Phase

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99252	Itolizumab		≥99.0%	Phase 3

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	CD6	NCBI	NCBI:923
Canis familiaris	CD6	NCBI	NCBI:483804
Macaca fascicularis	CD6	NCBI	NCBI:102143944
Mus musculus	CD6	NCBI	NCBI:12511
Susscrofa domestica	CD6	NCBI
Leporidae	CD6	NCBI
Macaca mulatta	CD6	NCBI	NCBI:695183

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