MGAT4C - MGAT4 family member C Gene

Homo sapiens

Also known as GNTIVH; HGNT-IV-H

Gene ID: 25834 | Gene type: protein coding

About MGAT4C

Cytogenetic location: 12q21.31-q21.32 Genomic coordinates (GRCh38): 12:85,955,667-86,839,000 (from NCBI)

This gene has 11 transcripts (splice variants), 1 gene allele, 270 orthologues and 3 paralogues. Biased expression in thyroid (RPKM 3.6), brain (RPKM 1.8) and 3 other tissues.

Summary

Predicted to enable acetylglucosaminyltransferase activity. Predicted to be involved in protein N-linked glycosylation. Predicted to be located in Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022]

MGAT4C Products(10)

mRNA	Protein	Name
NM_001351282.2	NP_001338211.1	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform a precursor
NM_001351283.2	NP_001338212.1	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform b
NM_001351284.2	NP_001338213.1	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform b
NM_001351285.2	NP_001338214.1	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform c
NM_001351286.2	NP_001338215.1	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform c
NM_001351287.2	NP_001338216.1	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform c
NM_001351288.2	NP_001338217.1	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform c
NM_001351289.2	NP_001338218.1	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform c
NM_001351291.2	NP_001338220.1	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform c
NM_013244.5	NP_037376.2	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform c

MGAT4C Protein Structure

Glyco_transf_54

0
100
200
300
400
478 a.a.

Protein Preferred Names

Protein Names

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

N-acetylglucosaminyltransferase IV homolog

Related Diseases

Diseases

Alias

Congenital Muscular Dystrophy-Dystroglycanopathy Type A11

Congenital Muscular Dystrophy-Dystroglycanopathy With Brain And Eye Anomalies Type A11	Mddga11
Walker-Warburg Syndrome Or Muscle-Eye-Brain Disease B3galnt2-Related	Congenital Muscular Dystrophy-Dystroglycanopathy With Brain And Eye Anomalies, Type A11

Walker-Warburg Syndrome

Hard Syndrome	Walker-Warburg Congenital Muscular Dystrophy
Cerebroocular Dysplasia-Muscular Dystrophy Syndrome	Cod-Md Syndrome
Chemke Syndrome	Hydrocephalus, Agyria And Retinal Dysplasia
Cerebroocular Dysgenesis	Cerebroocular Dysplasia Muscular Dystrophy Syndrome
Hard +/- E Syndrome	Pagon Syndrome
Warburg Syndrome	Hydrocephalus, Agyria, And Retinal Dysplasia
Mddga	Muscular Dystrophy-Dystroglycanopathy , Type A
Muscular Dystrophy-Dystroglycanopathy [With Brain And Eye Anomalies], Type A	Hydrocephalus-Agyria-Retinal Dysplasia Syndrome
Wws	Dystrophy, Muscular, Dystroglycanopathy, Type A

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect Pre-designed Sets	Purity	Rare Diseases Unkown
HY-RS08406	MGAT4C Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	MGAT4C	RGD	RGD:1307871
Macaca mulatta	MGAT4C	VGNC	VGNC:74628
Bos taurus	MGAT4C	VGNC	VGNC:31448
Canis familiaris	MGAT4C	VGNC	VGNC:54326
Felis catus	MGAT4C	VGNC	VGNC:63487
Mus musculus	MGAT4C	MGD	MGI:1914819

Name
Email *

	Sorry, but the email address you supplied was invalid.