ABI3BP - ABI family member 3 binding protein Gene

Homo sapiens

Also known as TARSH; NESHBP

Gene ID: 25890 | Gene type: protein coding

About ABI3BP

Cytogenetic location: 3q12.2 Genomic coordinates (GRCh38): 3:100,749,156-100,993,421 (from NCBI)

This gene has 28 transcripts (splice variants), 268 orthologues and 1 paralogue. Broad expression in gall bladder (RPKM 33.8), lung (RPKM 26.2) and 21 other tissues.

Summary

Predicted to enable actin filament binding activity and glycosaminoglycan binding activity. Predicted to be involved in regulation of actin Cytoskeleton reorganization; regulation of dendritic spine morphogenesis; and regulation of postsynaptic density assembly. Predicted to act upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in extracellular space. Colocalizes with collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

ABI3BP Products(11)

mRNA	Protein	Name
NM_001349329.2	NP_001336258.2	target of Nesh-SH3 isoform 1 precursor
NM_001349330.2	NP_001336259.2	target of Nesh-SH3 isoform 2 precursor
NM_001349331.2	NP_001336260.2	target of Nesh-SH3 isoform 3 precursor
NM_001349332.2	NP_001336261.2	target of Nesh-SH3 isoform 4 precursor
NM_001365642.2	NP_001352571.2	target of Nesh-SH3 isoform 6 precursor
NM_001365643.2	NP_001352572.2	target of Nesh-SH3 isoform 7 precursor
NM_001375547.2	NP_001362476.1	target of Nesh-SH3 isoform 8 precursor
NM_001375549.2	NP_001362478.1	target of Nesh-SH3 isoform 9 precursor
NM_001375550.1	NP_001362479.1	target of Nesh-SH3 isoform 10 precursor
NM_001377332.1	NP_001364261.1	target of Nesh-SH3 isoform 11 precursor
NM_015429.4	NP_056244.3	target of Nesh-SH3 isoform 5 precursor

ABI3BP Protein Structure

fn3

0
200
400
600
800
1000
1075 a.a.

Protein Preferred Names

Protein Names

target of Nesh-SH3

ABI family, member 3 (NESH) binding protein

Related Diseases

Diseases

Alias

Benign Pleural Mesothelioma

Mesothelioma Of Pleura	Benign Neoplasm Of Mesothelial Tissue Of Pleura
Pleural Malignant Mesothelioma

Agnathia-Otocephaly Complex

Otocephaly	Holoprosencephaly-Agnathia
Dysgnathia Complex Agnathia-Holoprosencephaly	AGOTC
Agnathia-Holoprosencephaly-Situs Inversus Syndrome	Dysgnathia Complex
Agnathia-Holoprosencephaly	Cervical Auricle

Fibrochondrogenesis

Fbcg1	Fbcg2
Fibrochondrogenesis-1	Fibrochondrogenesis-2
Fibrochondrogenesis 1	Fibrochondrogenesis 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00101	ABI3BP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ABI3BP	VGNC	VGNC:37477
Felis catus	ABI3BP	VGNC	VGNC:59489
Rattus norvegicus	ABI3BP	RGD	RGD:1562717
Macaca mulatta	ABI3BP	VGNC	VGNC:81175
Mus musculus	ABI3BP	MGD	MGI:2444583

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