SEC31B - SEC31 homolog B, COPII coat complex component Gene

Homo sapiens

Also known as SEC31L2; SEC31B-1

Gene ID: 25956 | Gene type: protein coding

About SEC31B

Cytogenetic location: 10q24.31 Genomic coordinates (GRCh38): 10:100,486,647-100,519,861 (from NCBI)

This gene has 13 transcripts (splice variants), 195 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 7.5), lymph node (RPKM 6.5) and 24 other tissues.

Summary

This gene encodes a protein of unknown function. The protein has moderate similarity to rat VAP1 protein which is an endosomal membrane-associated protein, containing a putative Ca2+/calmodulin-dependent kinase II phosphorylation site. [provided by RefSeq, Jul 2008]

SEC31B Products(1)

mRNA	Protein	Name
NM_015490.4	NP_056305.1	protein transport protein Sec31B

SEC31B Protein Structure

WD40

0
200
400
600
800
1000
1179 a.a.

Protein Preferred Names

Protein Names

protein transport protein Sec31B

SEC31 homolog B, COPII coating complex component

Related Diseases

Diseases

Alias

Retinitis Pigmentosa 47

RP47	Retinitis Pigmentosa, Type 47

Retinitis Pigmentosa 37

RP37	Retinitis Pigmentosa-37
Retinitis Pigmentosa, Type 37

Immunoglobulin A Deficiency 1

Immunoglobulin A Deficiency	Selective Iga Deficiency Disease
Selective Immunoglobulin A Deficiency	IGAD1
Immunoglobulin A, Selective Deficiency Of	Iga, Selective Deficiency Of
Gamma-A-Globulin, Selective Deficiency Of	Selective Iga Immunodeficiency
Selective Iga Deficiency	Iga Deficiency Selective

Hermansky-Pudlak Syndrome 1

Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells	HPS1
Delta Storage Pool Disease	Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial
Hermansky-Pudlak Syndrome, Type 1	Platelet Storage Pool Deficiency

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12620	SEC31B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SEC31B	VGNC	VGNC:77293
Canis familiaris	SEC31B	VGNC	VGNC:45977
Rattus norvegicus	SEC31B	RGD	RGD:1598329
Mus musculus	SEC31B	MGD	MGI:2685187
Bos taurus	SEC31B	VGNC	VGNC:34418
Felis catus	SEC31B	VGNC	VGNC:64972

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