Cadm4 - cell adhesion molecule 4 Gene

Mus musculus

Also known as Tsll2; Igdf4c; Igsf4c

Gene ID: 260299 | Gene type: protein coding

About Cadm4

Summary

Enables Enzyme binding activity and vascular endothelial growth factor receptor binding activity. Involved in several processes, including negative regulation of cellular response to growth factor stimulus; negative regulation of protein phosphorylation; and regulation of Rac protein signal transduction. Predicted to be located in cell leading edge and cell-cell contact zone. Is expressed in dorsal root ganglion; spinal cord; spinal cord gray matter; and spinal cord white matter. Orthologous to human CADM4 (cell adhesion molecule 4). [provided by Alliance of Genome Resources, Apr 2022]

Cadm4 Products(1)

mRNA	Protein	Name
NM_153112.3	NP_694752.1	cell adhesion molecule 4 precursor

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein phosphatase binding	IPI IPI: Inferred from physical interaction	23611113	MGI
enables receptor tyrosine kinase binding	IPI IPI: Inferred from physical interaction	23611113	MGI
enables vascular endothelial growth factor receptor 1 binding	IPI IPI: Inferred from physical interaction	25893857	MGI
enables vascular endothelial growth factor receptor 2 binding	IPI IPI: Inferred from physical interaction	25893857	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of peptidyl-threonine phosphorylation	IMP IMP: Inferred from mutant phenotype	23611113	MGI
involved in negative regulation of peptidyl-tyrosine phosphorylation	IMP IMP: Inferred from mutant phenotype	23611113	MGI
involved in negative regulation of protein phosphorylation	IMP IMP: Inferred from mutant phenotype	25893857	MGI
involved in negative regulation of vascular endothelial growth factor receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	25893857	MGI
involved in negative regulation of vascular endothelial growth factor signaling pathway	IMP IMP: Inferred from mutant phenotype	25893857	MGI
involved in regulation of Rac protein signal transduction	IMP IMP: Inferred from mutant phenotype	25893857	MGI
involved in regulation of cell motility	IMP IMP: Inferred from mutant phenotype	25893857	MGI
involved in regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	25893857	MGI
involved in regulation of protein phosphorylation	IMP IMP: Inferred from mutant phenotype	25893857	MGI
involved in regulation of wound healing	IMP IMP: Inferred from mutant phenotype	25893857	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cell adhesion molecule 4

NECL-4	SynCAM 4
TSLC1-like 2	TSLC1-like protein 2
immunoglobulin superfamily, member 4C	membrane glycoprotein Tsll2
nectin-like protein 4

Recombinant Cadm4 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76189	CADM4/IGSF4C Protein, Mouse (HEK293, His)	Q8R464 (P21-A324)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01822	CADM4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cadm4	NCBI	NCBI:199731

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