FGFR1OP2 - FGFR1 oncogene partner 2 Gene

Homo sapiens

Also known as WIT3.0; HSPC123-like

Gene ID: 26127 | Gene type: protein coding

About FGFR1OP2

Cytogenetic location: 12p11.23 Genomic coordinates (GRCh38): 12:26,938,470-26,966,648 (from NCBI)

This gene has 6 transcripts (splice variants), 220 orthologues and 1 paralogue. Ubiquitous expression in ovary (RPKM 23.0), adrenal (RPKM 22.0) and 25 other tissues.

Summary

Predicted to enable identical protein binding activity. Predicted to be involved in response to wounding. Predicted to act upstream of or within wound healing. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

FGFR1OP2 Products(3)

mRNA	Protein	Name
NM_001171887.2	NP_001165358.1	FGFR1 oncogene partner 2 isoform 2
NM_001171888.2	NP_001165359.1	FGFR1 oncogene partner 2 isoform 3
NM_015633.3	NP_056448.1	FGFR1 oncogene partner 2 isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FGFR1OP2 Protein Structure

SIKE

0
100
200
253 a.a.

Protein Preferred Names

Protein Names

FGFR1 oncogene partner 2

fibroblast growth factor receptor 1 oncogene partner 2

Related Diseases

Diseases

Alias

Myeloid And Lymphoid Neoplasms Associated With Fgfr1 Abnormalities

Lymphoblastic Lymphoma

Lymphoma, Lymphoblastic	Lymphoma Lymphoblastic
Precursor Cell Lymphoblastic Lymphoma	Precursor Cell Lymphoblastic Leukemia Lymphoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04914	FGFR1OP2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	FGFR1OP2	VGNC	VGNC:28986
Canis familiaris	FGFR1OP2	VGNC	VGNC:40858
Mus musculus	FGFR1OP2	MGD	MGI:1914779
Rattus norvegicus	FGFR1OP2	RGD	RGD:1303233
Felis catus	FGFR1OP2	VGNC	VGNC:97437
Macaca mulatta	FGFR1OP2	VGNC	VGNC:72551

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