2. Gene
  3. Mapk9 - mitogen-activated protein kinase 9 Gene

Mapk9 - mitogen-activated protein kinase 9 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as JNK2; Prkm9; p54aSAPK

Gene ID: 26420 | Gene type: protein coding

About Mapk9

Chromosome 11: 49,737,578-49,777,248 forward strand.GRCm39:CM001004.3

This gene has 10 transcripts (splice variants), 221 orthologues, 19 paralogues and is associated with 20 phenotypes. Ubiquitous expression in cerebellum adult (RPKM 32.4), cortex adult (RPKM 26.9) and 28 other tissues.

Summary

Enables protein serine/threonine/tyrosine kinase activity. Involved in peptidyl-serine phosphorylation; positive regulation of cellular protein metabolic process; and regulation of circadian rhythm. Acts upstream of or within several processes, including positive regulation of apoptotic signaling pathway; positive regulation of podosome assembly; and protein localization to tricellular tight junction. Located in cytosol and mitochondrion. Is expressed in several structures, including brain; extraembryonic component; future brain; genitourinary system; and spinal cord. Human ortholog(s) of this gene implicated in colorectal cancer; pancreatic adenocarcinoma; and type 2 diabetes mellitus. Orthologous to human MAPK9 (mitogen-activated protein kinase 9). [provided by Alliance of Genome Resources, Apr 2022]

Mapk9 Products(4)

mRNA Protein Name
NM_016961.3 NP_058657.1 mitogen-activated protein kinase 9 isoform beta1
NM_001163671.1 NP_001157143.1 mitogen-activated protein kinase 9 isoform beta2
NM_207692.2 NP_997575.2 mitogen-activated protein kinase 9 isoform alpha2
NM_001163672.1 NP_001157144.1 mitogen-activated protein kinase 9 isoform alpha1

Mapk9 Protein Structure

STKc_JNK

STKc_JNK: cd07850 (24 - 359)

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  • 423 a.a.
Protein Preferred Names Protein Names

mitogen-activated protein kinase 9

JNK/SAPK alpha

Jun kinase

MAP kinase 9

MAPK 9

c-Jun N-terminal kinase 2

protein kinase, mitogen-activated 9

stress-activated protein kinase JNK2

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148063 DB0614 98.80% Unkown
HY-148061 DB1113 99.28% Unkown
HY-RS08127 MAPK9 Human Pre-designed siRNA Set A / Unkown
HY-RS08128 Mapk9 Mouse Pre-designed siRNA Set A / Unkown
HY-RS08129 Mapk9 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mapk9 NCBI NCBI:5601