2. Gene
  3. Psma1 - proteasome subunit alpha 1 Gene

Psma1 - proteasome subunit alpha 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as C2; HC2; Pros-30; alpha-type

Gene ID: 26440 | Gene type: protein coding

About Psma1

Summary

Enables lipopolysaccharide binding activity. Involved in negative regulation of inflammatory response to antigenic stimulus. Part of Proteasome core complex. Is expressed in several structures, including alimentary system; brain ventricular layer; cranial ganglion; musculoskeletal system; and sensory organ. Orthologous to human PSMA1 (Proteasome 20S subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Psma1 Products(1)

mRNA Protein Name
NM_011965.2 NP_036095.1 proteasome subunit alpha type-1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables lipopolysaccharide binding IDA
IDA: Inferred from direct assay
12874245 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16973439 MGI
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of inflammatory response to antigenic stimulus IMP
IMP: Inferred from mutant phenotype
12874245 MGI
Cellular Component GO Annotation Evidence Reference Source
part of proteasome complex IDA
IDA: Inferred from direct assay
16973439 MGI
part of proteasome core complex IDA
IDA: Inferred from direct assay
16857966 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proteasome subunit alpha type-1

20S proteasome subunit C2

macropain subunit C2

multicatalytic endopeptidase complex subunit C2

proteasome (prosome, macropain) subunit, alpha type 1

proteasome component C2

proteasome nu chain

Psma1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Psma1 Q9R1P4 Zfand2b Mus musculus Q91X58
Anti Bait CoIP
18467495
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-117756 Piflufolastat 99.10% Phase 4
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-43869 Vipivotide tetraxetan Ligand-Linker Conjugate 99.95% Unkown
HY-P10055A PSMA targeting peptide TFA 99.09% Unkown
HY-162965 Immunoproteasome activator 1 Activator / Unkown
HY-RS11291 PSMA1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Psma1 NCBI NCBI:5682