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  3. STEAP1 - STEAP family member 1 Gene

STEAP1 - STEAP family member 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as STEAP; PRSS24

Gene ID: 26872 | Gene type: protein coding

About STEAP1

Cytogenetic location: 7q21.13 Genomic coordinates (GRCh38): 7:90,154,469-90,164,827 (from NCBI)

This gene has 3 transcripts (splice variants), 143 orthologues and 4 paralogues. Biased expression in prostate (RPKM 54.6), appendix (RPKM 20.3) and 9 other tissues.

Summary

This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple Cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions. [provided by RefSeq, Jul 2008]

STEAP1 Products(1)

mRNA Protein Name
NM_012449.3 NP_036581.1 metalloreductase STEAP1

STEAP1 Protein Structure

Ferric_reduct

Ferric_reduct: Ferric reductase like transmembrane component (119 - 263)

  • 0
  • 100
  • 200
  • 300
  • 339 a.a.
Protein Preferred Names Protein Names

metalloreductase STEAP1

STEAP1 metalloreductase

Recombinant STEAP1 Proteins

Cat. No. Product Name Accession Purity
HY-P78762 STEAP1 Protein, Human (HEK293, His) Q9UHE8 (Q2-L339) ≥95%

Related Diseases

Diseases Alias
Deficiency Anemia

Anemia

Deficiency Anemias

Anaemia
Aceruloplasminemia

Cerebellar Ataxia

Hypoceruloplasminemia

Hemosiderosis, Systemic, Due To Aceruloplasminemia

Familial Apoceruloplasmin Deficiency

Hereditary Ceruloplasmin Deficiency

Deficiency Of Ferroxidase

Hypoceruloplasminemia, Hereditary

Ceruloplasmin Deficiency

Systemic Hemosiderosis Due To Aceruloplasminemia

ACERULOP
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-138635 PROTAC BRD4 Degrader-12 Inhibitor 99.85% Unkown
HY-138634 PROTAC BRD4 Degrader-11 Inhibitor 99.45% Unkown
HY-138632 PROTAC BRD4 Degrader-9 Inhibitor 98.23% Unkown
HY-138636 PROTAC BRD4 Degrader-13 Degrader / Unkown
HY-138633 PROTAC BRD4 Degrader-10 Inhibitor 99.75% Unkown
HY-RS13905 STEAP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13906 STEAP1B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus STEAP1 MGD MGI:1917608
Rattus norvegicus STEAP1 RGD RGD:1311543