DKKL1 - dickkopf like acrosomal protein 1 Gene

Homo sapiens

Also known as SGY; CT34; SGY1; SGY-1

Gene ID: 27120 | Gene type: protein coding

About DKKL1

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:49,360,515-49,375,116 (from NCBI)

This gene has 6 transcripts (splice variants) and 92 orthologues. Restricted expression toward testis (RPKM 49.6).

Summary

The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

DKKL1 Products(3)

mRNA	Protein	Name
NM_001197301.2	NP_001184230.1	dickkopf-like protein 1 isoform 2 precursor
NM_001197302.2	NP_001184231.1	dickkopf-like protein 1 isoform 3
NM_014419.4	NP_055234.1	dickkopf-like protein 1 isoform 1 precursor

Protein Preferred Names

Protein Names

dickkopf-like protein 1

cancer/testis antigen 34

Related Diseases

Diseases

Alias

Rectum Adenocarcinoma

Rectal Adenocarcinoma

Adenocarcinoma Of Rectum

Rectal Benign Neoplasm

Neoplasm Of Rectum	Rectal Tumor
Rectum Neoplasm	Neoplasm Of The Rectum
Rectal Neoplasms	Primary Rectal Cancer
Rectal Ampulla Cancer	Cancer Of The Rectum
Carcinoma Of Rectum	Primary Malignant Neoplasm Of Rectum
Rectal Cancer	Rectal Carcinoma

Trachea Carcinoma

Pancoast Tumor	Carcinoma Of The Trachea
Pancoast'S Tumor	Malignant Superior Sulcus Tumor
Malignant Superior Sulcus Tumour	Pancoast Tumour
Pancoast'S Syndrome	Pancoast'S Tumour
Pulmonary Sulcus Tumor	Pulmonary Sulcus Tumour
Superior Pulmonary Sulcus Syndrome	Pancoast Syndrome

Rectum Cancer

Malignant Neoplasm Of Rectum	Rectal Cancer
Cancer Of Rectum	Carcinoma Of Rectum
Carcinoma Of The Rectum	Malignant Rectal Tumor
Malignant Rectum Tumor	Malignant Tumor Of Rectum
Rectal Carcinoma	Rectal Cancers
Cancer, Rectal

Male Infertility

Infertility, Male	Infertility Male
Male Sterility	Absolute Infertility

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03791	DKKL1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	DKKL1	RGD	RGD:1563523
Felis catus	DKKL1	VGNC	VGNC:61507
Canis familiaris	DKKL1	VGNC	VGNC:39973
Macaca mulatta	DKKL1	VGNC	VGNC:109615
Bos taurus	DKKL1	VGNC	VGNC:28083
Mus musculus	DKKL1	MGD	MGI:1354963

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