ZNF638 - zinc finger protein 638 Gene

Homo sapiens

Also known as ZFML; NP220; Zfp638

Gene ID: 27332 | Gene type: protein coding

About ZNF638

Cytogenetic location: 2p13.2 Genomic coordinates (GRCh38): 2:71,331,782-71,435,061 (from NCBI)

This gene has 27 transcripts (splice variants), 174 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 14.1), thyroid (RPKM 11.9) and 25 other tissues.

Summary

The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

ZNF638 Products(4)

mRNA	Protein	Name
NM_001014972.3	NP_001014972.1	zinc finger protein 638 isoform 1
NM_001252612.2	NP_001239541.1	zinc finger protein 638 isoform 1
NM_001252613.2	NP_001239542.1	zinc finger protein 638 isoform 2
NM_014497.5	NP_055312.2	zinc finger protein 638 isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32814053	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF638 Protein Structure

0
400
800
1200
1600
1978 a.a.

Protein Preferred Names

Protein Names

zinc finger protein 638

CTCL tumor antigen se33-1

Related Diseases

Diseases

Alias

Lymphoma

Lymphoid Cancer	Lymphomas
Lymphoid Cancers	Lymphoid Neoplasm
Lymphoma Nos	Nhl - [Non-Hodgkin Lymphoma]
Non-Hodgkin Lymphoma	Non-Hodgkin Lymphoma, Nos
Non-Hodgkin Malignant Lymphoma Nos

Acromesomelic Dysplasia 2b

Fibular Hypoplasia And Complex Brachydactyly	Du Pan Syndrome
AMD2B	Dupans
Acromesomelic Dysplasia-2b	Fibular Aplasia-Complex Brachydactyly Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect Pre-designed Sets	Purity	Rare Diseases Unkown
HY-RS16161	ZNF638 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ZNF638	MGD	MGI:1203484
Bos taurus	ZNF638	VGNC	VGNC:37318
Felis catus	ZNF638	VGNC	VGNC:67340
Macaca mulatta	ZNF638	VGNC	VGNC:79098
Canis familiaris	ZNF638	VGNC	VGNC:48781
Rattus norvegicus	ZNF638	RGD	RGD:1309746

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