Vsig4 - V-set and immunoglobulin domain containing 4 Gene

Mus musculus

Also known as CRIg; Z39IG; A530061A11

Gene ID: 278180 | Gene type: protein coding

About Vsig4

Summary

Predicted to enable complement component C3b binding activity. Acts upstream of or within negative regulation of T cell proliferation and negative regulation of interleukin-2 production. Predicted to be part of protein-containing complex. Is expressed in bone marrow; oviduct; and thyroid gland. Orthologous to human VSIG4 (V-set and immunoglobulin domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]

Vsig4 Products(1)

mRNA	Protein	Name
NM_177789.5	NP_808457.1	V-set and immunoglobulin domain-containing protein 4 precursor

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within negative regulation of T cell proliferation	IDA IDA: Inferred from direct assay	17016562	MGI
acts upstream of or within negative regulation of interleukin-2 production	IDA IDA: Inferred from direct assay	17016562	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

V-set and immunoglobulin domain-containing protein 4

complement receptor of the immunoglobulin superfamily

Recombinant Vsig4 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71006	VSIG4 Protein, Mouse (HEK293, His)	F6TUL9 (H20-P187)	≥95%
HY-P76699	VSIG4 Protein, Mouse (HEK293, His-Fc)	F6TUL9 (H20-P187)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15709	VSIG4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Vsig4	NCBI	NCBI:11326
Macaca fascicularis	Vsig4	NCBI	NCBI:102144784

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