2. Gene
  3. AMY2B - amylase alpha 2B Gene

AMY2B - amylase alpha 2B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HXA; AMY2; AMY3

Gene ID: 280 | Gene type: protein coding

About AMY2B

Cytogenetic location: 1p21.1 Genomic coordinates (GRCh38): 1:103,554,644-103,579,534 (from NCBI)

This gene has 9 transcripts (splice variants), 194 orthologues and 7 paralogues. Biased expression in pancreas (RPKM 6104.1) and salivary gland (RPKM 774.6).

Summary

Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and Polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas. [provided by RefSeq, Jun 2013]

AMY2B Products(3)

mRNA Protein Name
NM_001386109.1 NP_001373038.1 alpha-amylase 2B precursor
NM_001387437.1 NP_001374366.1 alpha-amylase 2B precursor
NM_020978.4 NP_066188.1 alpha-amylase 2B precursor

AMY2B Protein Structure

Alpha-amylase

Alpha-amylase: Alpha amylase, catalytic domain (46 - 345)

Alpha-amylase_C

Alpha-amylase_C: Alpha amylase, C-terminal all-beta domain (425 - 505)

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  • 511 a.a.
Protein Preferred Names Protein Names

alpha-amylase 2B

1,4-alpha-D-glucan glucanohydrolase 2B

Recombinant AMY2B Proteins

Cat. No. Product Name Accession Purity
HY-P7500 AMY2B Protein, Human (HEK293, His) P19961 (Q16-L511) ≥95%

Related Diseases

Diseases Alias
Ichthyosis, Congenital, Autosomal Recessive 10

Autosomal Recessive Congenital Ichthyosis 10

ARCI10

Ichthyosis, Congenital, Autosomal Recessive, Type 10
Occupational Asthma
Environmental Induced Asthma

Irritant Asthma
Tick Infestation

Tick Infestations
Chromosome 1p36 Deletion Syndrome

1p36 Deletion Syndrome

Deletion 1p36

Monosomy 1p36

Subtelomeric 1p36 Deletion

Monosomy 1p36 Syndrome

Distal Monosomy 1p36

Del(1)(P36)

Deletion 1pter

Monosomy 1pter
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00674 AMY2B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus AMY2B RGD RGD:2113
Others AMY2B NCBI