B4GALNT3 - beta-1,4-N-acetyl-galactosaminyltransferase 3 Gene

Homo sapiens

Gene ID: 283358 | Gene type: protein coding

About B4GALNT3

Cytogenetic location: 12p13.33 Genomic coordinates (GRCh38): 12:459,939-563,509 (from NCBI)

This gene has 7 transcripts (splice variants), 198 orthologues and 7 paralogues. Biased expression in stomach (RPKM 33.1), colon (RPKM 16.3) and 11 other tissues.

Summary

B4GALNT3 transfers N-acetylgalactosamine (GalNAc) onto glucosyl residues to form N,N-prime-diacetyllactosediamine (LacdiNAc, or LDN), a unique terminal structure of cell surface N-glycans (Ikehara et al., 2006 [PubMed 16728562]).[supplied by OMIM, Aug 2008]

B4GALNT3 Products(1)

mRNA	Protein	Name
NM_173593.4	NP_775864.3	beta-1,4-N-acetylgalactosaminyltransferase 3

B4GALNT3 Protein Structure

PA14

CHGN

0
200
400
600
800
998 a.a.

Protein Preferred Names

Protein Names

beta-1,4-N-acetylgalactosaminyltransferase 3

B4GalNAcT3

Related Diseases

Diseases

Alias

Idiopathic Peripheral Autonomic Neuropathy

Chronic Polyneuropathy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01317	B4GALNT3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	B4GALNT3	RGD	RGD:1561056
Mus musculus	B4GALNT3	MGD	MGI:3041155
Macaca mulatta	B4GALNT3	VGNC	VGNC:70121
Felis catus	B4GALNT3	VGNC	VGNC:60064
Bos taurus	B4GALNT3	VGNC	VGNC:26387
Canis familiaris	B4GALNT3	VGNC	VGNC:38347

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