PRTG - protogenin Gene

Homo sapiens

Also known as IGDCC5

Gene ID: 283659 | Gene type: protein coding

About PRTG

Cytogenetic location: 15q21.3 Genomic coordinates (GRCh38): 15:55,611,544-55,743,152 (from NCBI)

This gene has 6 transcripts (splice variants), 201 orthologues and 36 paralogues. Biased expression in thyroid (RPKM 4.7), endometrium (RPKM 1.7) and 7 other tissues.

Summary

This gene encodes a member of the immunoglobulin superfamily. The encoded transmembrane protein has been associated with the development of various tissues, especially neurogenesis. It has been suggested that this gene may be associated with attention deficit hyperactivity disorder (ADHD). [provided by RefSeq, Nov 2014]

PRTG Products(1)

mRNA	Protein	Name
NM_173814.6	NP_776175.2	protogenin precursor

PRTG Protein Structure

I-set

fn3

0
200
400
600
800
1000
1150 a.a.

Protein Preferred Names

Protein Names

protogenin

immunoglobulin superfamily, DCC subclass, member 5

Related Diseases

Diseases

Alias

Orofacial Cleft 5

OFC5	Cleft Lip With Or Without Cleft Palate, Nonsyndromic, 5
Nonsyndromic Cleft Lip With Or Without Cleft Palate 5	Non-Syndromic Orofacial Cleft 5
Non-Syndromic Cleft Lip/Palate 5	Non-Syndromic Cleft Lip With Or Without Cleft Palate 5
Orofacial Cleft, Type 5

Orofacial Cleft 10

OFC10	Cleft Lip With Or Without Cleft Palate, Nonsyndromic, 10
Nonsyndromic Cleft Lip With Or Without Cleft Palate 10	Non-Syndromic Orofacial Cleft 10
Non-Syndromic Cleft Lip/Palate 10	Non-Syndromic Cleft Lip With Or Without Cleft Palate 10
Orofacial Cleft, Type 10

Orofacial Cleft 11

OFC11	Cleft Lip With Or Without Cleft Palate, Nonsyndromic, 11
Nonsyndromic Cleft Lip With Or Without Cleft Palate 11	Non-Syndromic Orofacial Cleft 11
Chcl	Cleft Lip Congenital Healed
Congenital Healed Cleft Lip	Non-Syndromic Cleft Lip/Palate 11
Non-Syndromic Cleft Lip With Or Without Cleft Palate 11	Orofacial Cleft, Type 11
Cleft Lip, Congenital Healed

Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder	ADHD
Attention Deficit Disorder	Attention Deficit-Hyperactivity Disorder, Susceptibility To
Attention Deficit Disorder With Hyperactivity	Hyperkinetic Disorder
Hyperactivity Of Childhood	Attention-Deficit/Hyperactivity Disorder
Add	Addh
Attention Deficit	Attention Deficit Disorder Of Childhood With Hyperactivity
Attention Deficit Disorder With Hyperactivity Syndrome	Hyperkinetic Syndrome
Attention-Deficit Hyperactivity Disorder	Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type
Disturbance Of Activity And Attention	Disorder Of Activity And Attention
Adhd - [Attention Deficit Hyperactivity Disorder]	Hyperkinetic Disorders
Disorder Of Activity And Attention With Hyperkinesia	Attention Deficit Syndrome With Hyperactivity

Orofacial Cleft 15

OFC15

Non-Syndromic Orofacial Cleft 15

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11261	PRTG Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PRTG	VGNC	VGNC:55137
Felis catus	PRTG	VGNC	VGNC:64405
Mus musculus	PRTG	MGD	MGI:2444710
Rattus norvegicus	PRTG	RGD	RGD:1307157
Macaca mulatta	PRTG	VGNC	VGNC:76321
Canis familiaris	PRTG	VGNC	VGNC:45076

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