2. Gene
  3. SAXO2 - stabilizer of axonemal microtubules 2 Gene

SAXO2 - stabilizer of axonemal microtubules 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as FAM154B

Gene ID: 283726 | Gene type: protein coding

About SAXO2

This gene has 9 transcripts (splice variants), 152 orthologues and 1 paralogue. Biased expression in lung (RPKM 3.6), testis (RPKM 1.5) and 13 other tissues.

Summary

Predicted to enable microtubule binding activity. Predicted to be involved in microtubule anchoring. Predicted to be active in microtubule cytoskeleton; nucleus; and sperm flagellum. [provided by Alliance of Genome Resources, Apr 2022]

SAXO2 Products(9)

mRNA Protein Name
NM_001008226.2 NP_001008227.1 stabilizer of axonemal microtubules 2 isoform c
NM_001348699.2 NP_001335628.1 stabilizer of axonemal microtubules 2 isoform a
NM_001348700.2 NP_001335629.1 stabilizer of axonemal microtubules 2 isoform b
NM_001348701.2 NP_001335630.1 stabilizer of axonemal microtubules 2 isoform b
NM_001348702.2 NP_001335631.1 stabilizer of axonemal microtubules 2 isoform d
NM_001348703.2 NP_001335632.1 stabilizer of axonemal microtubules 2 isoform d
NM_001348704.2 NP_001335633.1 stabilizer of axonemal microtubules 2 isoform e
NM_001348705.2 NP_001335634.1 stabilizer of axonemal microtubules 2 isoform f
NM_001348706.2 NP_001335635.1 stabilizer of axonemal microtubules 2 isoform g
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SAXO2 Protein Structure

STOP

STOP: STOP protein (9 - 221)

STOP

STOP: STOP protein (216 - 294)

STOP

STOP: STOP protein (285 - 363)

  • 0
  • 100
  • 200
  • 300
  • 398 a.a.
Protein Preferred Names Protein Names

stabilizer of axonemal microtubules 2

family with sequence similarity 154, member B

SAXO2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
SAXO2 Q658L1 FBXO17 Homo sapiens Q96EF6
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12462 SAXO2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SAXO2 VGNC VGNC:64884
Mus musculus SAXO2 MGD MGI:1914618
Bos taurus SAXO2 VGNC VGNC:34302
Canis familiaris SAXO2 VGNC VGNC:45879
Rattus norvegicus SAXO2 RGD RGD:1562653