2. Gene
  3. GPR22 - G protein-coupled receptor 22 Gene

GPR22 - G protein-coupled receptor 22 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 2845 | Gene type: protein coding

About GPR22

Cytogenetic location: 7q22.3 Genomic coordinates (GRCh38): 7:107,470,057-107,477,845 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 226 orthologues and 16 paralogues. Biased expression in heart (RPKM 6.9), brain (RPKM 4.8) and 2 other tissues.

Summary

This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein. [provided by RefSeq, Jul 2008]

GPR22 Products(1)

mRNA Protein Name
NM_005295.3 NP_005286.2 G-protein coupled receptor 22
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables G protein-coupled receptor activity IMP
IMP: Inferred from mutant phenotype
18539757 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPR22 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (59 - 367)

  • 0
  • 100
  • 200
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  • 400
  • 433 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 22

probable G-protein coupled receptor 22

Related Diseases

Diseases Alias
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes

Melas Syndrome

MELAS

Mitochondrial Encephalomyopathy Lactic Acidosis And Stroke-Like Episodes

Mitochondrial Myopathy, Lactic Acidosis, Stroke-Like Episode

Mitochondrial Encephalomyopathy, Lactic Acidosis, And Stroke-Like Episodes

Myopathy, Mitochondrial-Encephalopathy-Lactic Acidosis-Stroke

Mitochondrial Encephalomyopathy, Lactic Acidosis And Stroke-Like Episodes

Mitochondrial Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes

Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis And Stroke-Like Episodes

Mitochondrial Encephalomyopathy With Lactic Acidosis And Stroke-Like Episodes Syndrome

Myopathy, Mitochondrial, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05696 GPR22 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus GPR22 RGD RGD:1310848
Macaca mulatta GPR22 VGNC VGNC:73129
Canis familiaris GPR22 VGNC VGNC:41426
Mus musculus GPR22 MGD MGI:1920260
Felis catus GPR22 VGNC VGNC:67421
Bos taurus GPR22 VGNC VGNC:29580