2. Gene
  3. GPR27 - G protein-coupled receptor 27 Gene

GPR27 - G protein-coupled receptor 27 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SREB1

Gene ID: 2850 | Gene type: protein coding

About GPR27

Cytogenetic location: 3p13 Genomic coordinates (GRCh38): 3:71,753,855-71,756,496 (from NCBI)

This gene has 1 transcript (splice variant), 156 orthologues and 2 paralogues.

Summary

GPR27 is a member of the G protein-coupled receptors (GPCRs), a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, Hormones, or LIGHT induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins.[supplied by OMIM, May 2010]

GPR27 Products(1)

mRNA Protein Name
NM_018971.3 NP_061844.1 probable G-protein coupled receptor 27

GPR27 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (35 - 337)

  • 0
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  • 300
  • 375 a.a.
Protein Preferred Names Protein Names

probable G-protein coupled receptor 27

super conserved receptor expressed in brain 1

Related Diseases

Diseases Alias
Eyelid Disease

Eyelid Diseases

Eyelid Disorders
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-163087 PT-91 98.25% Unkown
HY-114146 CID 1375606 Inhibitor 99.90% Unkown
HY-164814 GPR27 agonist-1 / Unkown
HY-RS05699 GPR27 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GPR27 MGD MGI:1202299
Rattus norvegicus GPR27 RGD RGD:71067
Felis catus GPR27 VGNC VGNC:102594
Macaca mulatta GPR27 VGNC VGNC:84175
Bos taurus GPR27 VGNC VGNC:106758