CDH19 - cadherin 19 Gene

Homo sapiens

Also known as CDH7; CDH7L2

Gene ID: 28513 | Gene type: protein coding

About CDH19

Cytogenetic location: 18q22.1 Genomic coordinates (GRCh38): 18:66,501,083-66,604,090 (from NCBI)

This gene has 5 transcripts (splice variants), 125 orthologues and 33 paralogues. Broad expression in heart (RPKM 5.1), adrenal (RPKM 2.5) and 19 other tissues.

Summary

This gene is one of three related type II cadherin genes situated in a cluster on chromosome 18. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein containing five extracellular cadherin repeats. Loss of Cadherins may be associated with Cancer formation. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Aug 2012]

CDH19 Products(2)

mRNA	Protein	Name
NM_001271028.2	NP_001257957.1	cadherin-19 isoform 2 preproprotein
NM_021153.4	NP_066976.1	cadherin-19 isoform 1 preproprotein

CDH19 Protein Structure

Cadherin

Cadherin_C

0
200
400
600
772 a.a.

Protein Preferred Names

Protein Names

cadherin-19

cadherin 19, type 2

Recombinant CDH19 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P700973	CDH19 Protein, Human (Flag-MBP)	Q9H159-1 (G44-H569)	≥95%

Related Diseases

Diseases

Alias

Achilles Bursitis

Achilles Bursitis Or Tendinitis	Capped Hock
Haglund'S Deformity	Haglund'S Disease
Osteochondritis Of The Talus

Craniofacial-Deafness-Hand Syndrome

CDHS	Craniofacial Deafness Hand Syndrome
Sommer-Young-Wee-Frye Syndrome	Features Of Flat Facial Profile, Hypertelorism, Hypoplastic Nose With Slitlike Nares, And A Sensorineural Hearing Loss
Craniofacial-Hearing Loss-Hand Syndrome

Choanal Atresia, Posterior

Choanal Atresia	Atresia Of Nares
Posterior Choanal Atresia	PCA
Imperforate Nares	Choanal Fusion
Congenital Stenosis Of Nares	Congenital Stenosis Of Choanae
Nasal Atresia Nos

Charge Syndrome

Charge Association	Hall-Hittner Syndrome
Charge Association--Coloboma, Heart Anomaly, Choanal Atresia, Retardation, Genital And Ear Anomalies	Hhs
Coloboma, Heart Anomaly, Choanal Atresia, Restriction Of Growth And Development, Genital And Ear Anomalies	Coloboma-Heart Defects-Atresia Choanae-Retardation Of Growth And Development-Genitourinary Problems-Ear Abnormalities Syndrome
CHARGES

Coloboma Of Macula

Coloboma	Congenital Ocular Coloboma
Microphthalmia, Isolated, With Coloboma	Agenesis Of Macula
Hereditary Macular Coloboma	Ocular Coloboma
Coloboma Of Eye	Macular Coloboma
Uveoretinal Coloboma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect Pre-designed Sets	Purity	Rare Diseases Unkown
HY-RS02329	CDH19 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CDH19	VGNC	VGNC:60677
Rattus norvegicus	CDH19	RGD	RGD:1307169
Mus musculus	CDH19	MGD	MGI:3588198
Canis familiaris	CDH19	VGNC	VGNC:39027
Macaca mulatta	CDH19	VGNC	VGNC:70812
Others	CDH19	NCBI

Name
Email *

	Sorry, but the email address you supplied was invalid.