2. Gene
  3. LCN12 - lipocalin 12 Gene

LCN12 - lipocalin 12 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 286256 | Gene type: protein coding

About LCN12

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:136,949,197-136,956,538 (from NCBI)

This gene has 15 transcripts (splice variants), 156 orthologues and 12 paralogues. Biased expression in thyroid (RPKM 11.7), spleen (RPKM 1.8) and 4 other tissues.

Summary

Members of the Lipocalin Family, such as LCN12, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]

LCN12 Products(1)

mRNA Protein Name
NM_178536.4 NP_848631.2 epididymal-specific lipocalin-12 precursor

LCN12 Protein Structure

Lipocalin

Lipocalin: Lipocalin / cytosolic fatty-acid binding protein family (40 - 183)

  • 0
  • 100
  • 192 a.a.
Protein Preferred Names Protein Names

epididymal-specific lipocalin-12

epididymis secretory sperm binding protein

Related Diseases

Diseases Alias
Extratemporal Epilepsy
Corneal Ectasia
Keratoconus

Kc

Conical Cornea

Noninflammatory Corneal Thining

Bulging Cornea

Cornea Conical

Acquired Conus Of Cornea
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07556 LCN12 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta LCN12 VGNC VGNC:74143
Bos taurus LCN12 VGNC VGNC:59222
Mus musculus LCN12 MGD MGI:1924951
Rattus norvegicus LCN12 RGD RGD:1589474
Canis familiaris LCN12 VGNC VGNC:55626