2. Gene
  3. REM1 - RRAD and GEM like GTPase 1 Gene

REM1 - RRAD and GEM like GTPase 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GES; GD:REM

Gene ID: 28954 | Gene type: protein coding

About REM1

Cytogenetic location: 20q11.21 Genomic coordinates (GRCh38): 20:31,475,288-31,484,895 (from NCBI)

This gene has 1 transcript (splice variant), 169 orthologues and 35 paralogues. Broad expression in fat (RPKM 3.0), endometrium (RPKM 2.6) and 21 other tissues.

Summary

The protein encoded by this gene is a GTPase and member of the RAS-like GTP-binding protein family. The encoded protein is expressed in endothelial cells, where it promotes reorganization of the actin Cytoskeleton and morphological changes in the cells. [provided by RefSeq, Jul 2008]

REM1 Products(1)

mRNA Protein Name
NM_014012.6 NP_054731.2 GTP-binding protein REM 1

REM1 Protein Structure

Ras

Ras: Ras family (82 - 243)

  • 0
  • 100
  • 200
  • 298 a.a.
Protein Preferred Names Protein Names

GTP-binding protein REM 1

GTPase-regulating endothelial cell sprouting

Related Diseases

Diseases Alias
Mobitz Type Ii Atrioventricular Block

Mobitz Ii Atrioventricular Block

Mobitz Ii Atrioventricular Block
Immunodeficiency 18

IMD18

Cd3-Epsilon Deficiency

Immunodeficiency 18, Scid Variant

Cd3epsilon Deficiency

Immunodeficiency 18, Severe Combined Immunodeficiency Variant

Immunodeficiency, Type 18
Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11837 REM1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus REM1 VGNC VGNC:33863
Macaca mulatta REM1 VGNC VGNC:108026
Mus musculus REM1 MGD MGI:1097696
Canis familiaris REM1 VGNC VGNC:45472
Rattus norvegicus REM1 RGD RGD:1306560
Felis catus REM1 VGNC VGNC:64569
Others REM1 NCBI