2. Gene
  3. TMPRSS11E - transmembrane serine protease 11E Gene

TMPRSS11E - transmembrane serine protease 11E Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as DESC1; TMPRSS11E2

Gene ID: 28983 | Gene type: protein coding

About TMPRSS11E

Cytogenetic location: 4q13.2 Genomic coordinates (GRCh38): 4:68,447,463-68,497,604 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 338 orthologues and 17 paralogues. Restricted expression toward esophagus (RPKM 128.8).

Summary

Predicted to enable serine-type peptidase activity. Involved in cognition. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMPRSS11E Products(1)

mRNA Protein Name
NM_014058.4 NP_054777.2 transmembrane protease serine 11E precursor

TMPRSS11E Protein Structure

SEA

SEA: SEA domain (49 - 156)

Trypsin

Trypsin: Trypsin (192 - 417)

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  • 423 a.a.
Protein Preferred Names Protein Names

transmembrane protease serine 11E

serine protease DESC1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14766 TMPRSS11E Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TMPRSS11E VGNC VGNC:78423
Rattus norvegicus TMPRSS11E RGD RGD:1561698
Mus musculus TMPRSS11E MGD MGI:3513175