2. Gene
  3. Epha3 - Eph receptor A3 Gene

Epha3 - Eph receptor A3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 29210 | Gene type: protein coding

About Epha3

Summary

Predicted to enable GPI-linked Ephrin Receptor activity; growth factor binding activity; and transmembrane-ephrin receptor activity. Involved in fever generation; response to cytokine; and response to lipopolysaccharide. Predicted to be located in several cellular components, including GABA-ergic synapse; early endosome; and nucleus. Predicted to be part of receptor complex. Predicted to be active in neuron projection and presynapse. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human EphA3 (EPH receptor A3). [provided by Alliance of Genome Resources, Apr 2022]

Epha3 Products(1)

mRNA Protein Name
NM_031564.2 NP_113752.2 ephrin type-A receptor 3 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to interleukin-1 IEP
IEP: Inferred from expression pattern
9458884 RGD
involved in fever generation IEP
IEP: Inferred from expression pattern
15671251 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
15671251 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ephrin type-A receptor 3

EK4

EPH-like kinase 4

rEK4

tyrosine-protein kinase TYRO4

tyrosine-protein kinase receptor REK4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-163835 UniPR1454 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Epha3 NCBI NCBI:2042
Canis familiaris Epha3 NCBI NCBI:487930
Mus musculus Epha3 NCBI NCBI:13837