2. Gene
  3. Gdf15 - growth differentiation factor 15 Gene

Gdf15 - growth differentiation factor 15 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 29455 | Gene type: protein coding

About Gdf15

Summary

Enables protein homodimerization activity. Predicted to be involved in several processes, including Enzyme linked receptor protein signaling pathway; reduction of food intake in response to dietary excess; and regulation of signal transduction. Predicted to act upstream of or within positive regulation of myoblast fusion. Located in extracellular region. Orthologous to human GDF15 (Growth Differentiation Factor 15). [provided by Alliance of Genome Resources, Apr 2022]

Gdf15 Products(2)

mRNA Protein Name
NM_001411583.1 NP_001398512.1 growth/differentiation factor 15 precursor
NM_019216.3 NP_062089.2 growth/differentiation factor 15 precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
29046435 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular region IDA
IDA: Inferred from direct assay
29046435 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

growth/differentiation factor 15

GDF-15

Recombinant Gdf15 Proteins

Cat. No. Product Name Accession Purity
HY-P700727 GDF-15 Protein, Rat (His) Q9Z0J6 (S189-A303) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99241 Ponsegromab Inhibitor 95.00% Phase 2
HY-P99100 Visugromab 98.40% Phase 2
Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-149406 AMPK activator 12 Activator 99.68% Unkown
HY-RS05352 GDF15 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gdf15 NCBI NCBI:9518
Canis familiaris Gdf15 NCBI NCBI:484822
Macaca fascicularis Gdf15 NCBI NCBI:102117226
Mus musculus Gdf15 NCBI NCBI:23886