NXPH1 - neurexophilin 1 Gene

Homo sapiens

Also known as NPH1; Nbla00697

Gene ID: 30010 | Gene type: protein coding

About NXPH1

Cytogenetic location: 7p21.3 Genomic coordinates (GRCh38): 7:8,433,609-8,752,961 (from NCBI)

This gene has 5 transcripts (splice variants), 272 orthologues and 3 paralogues. Biased expression in adrenal (RPKM 15.5) and brain (RPKM 12.8).

Summary

This gene is a member of the neurexophilin family and encodes a secreted protein with a variable N-terminal domain, a highly conserved, N-glycosylated central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. [provided by RefSeq, Jul 2008]

NXPH1 Products(1)

mRNA	Protein	Name
NM_152745.3	NP_689958.1	neurexophilin-1 precursor

NXPH1 Protein Structure

Neurexophilin

0
100
200
271 a.a.

Protein Preferred Names

Protein Names

neurexophilin-1

Recombinant NXPH1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71178	NXPH1 Protein, Human (HEK293, His)	P58417 (A22-G271)	≥95%

Related Diseases

Diseases

Alias

Constipation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09717	NXPH1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	NXPH1	MGD	MGI:107492
Bos taurus	NXPH1	VGNC	VGNC:50069
Felis catus	NXPH1	VGNC	VGNC:63939
Rattus norvegicus	NXPH1	RGD	RGD:3218
Canis familiaris	NXPH1	VGNC	VGNC:44077
Macaca mulatta	NXPH1	VGNC	VGNC:81732
Others	NXPH1	NCBI

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