1. Gene
  2. Ezh1 - enhancer of zeste 1 polycomb repressive complex 2 subunit Gene

Ezh1 - enhancer of zeste 1 polycomb repressive complex 2 subunit Gene

Rattus norvegicus
Gene ID: 303547 | Gene type: protein coding

About Ezh1

Primary_assembly 10: 86,126,015-86,161,921 reverse strand.mRatBN7.2:CM026983.1

This gene has 2 transcripts (splice variants), 234 orthologues and 23 paralogues. Biased expression in Kidney (RPKM 177.3), Lung (RPKM 163.3) and 9 other tissues.

Summary

Enables chromatin binding activity. Involved in hippocampus development and positive regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human EZH1 (enhancer of zeste 1 polycomb repressive complex 2 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Ezh1 Products(1)

mRNA Protein Name
NM_001107051.1 NP_001100521.1 histone-lysine N-methyltransferase EZH1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables chromatin binding IDA
IDA: Inferred from direct assay
23932971 RGD
Biological Process GO Annotation Evidence Reference Source
involved in hippocampus development IEP
IEP: Inferred from expression pattern
23932971 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
23932971 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Ezh1 Protein Structure

EZH2_WD-Binding

EZH2_WD-Binding: pfam11616 (38 - 67)

PRC2_HTH_1

PRC2_HTH_1: pfam18118 (158 - 261)

SANT

SANT: cd00167 (432 - 473)

SET

SET: cl34524 (462 - 726)

SET_EZH1

SET_EZH1: cd19217 (607 - 742)

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  • 200
  • 400
  • 600
  • 747 a.a.
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase EZH1

enhancer of zeste homolog 1

Orthologs Information

Species Symbol Source ID
Homo sapiens Ezh1 NCBI NCBI:2145