2. Gene
  3. Fcgr3a - Fc gamma receptor 3A Gene

Fcgr3a - Fc gamma receptor 3A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Fcgr4; CD16-2

Gene ID: 304966 | Gene type: protein coding

About Fcgr3a

Summary

Predicted to enable IgE receptor activity and IgG receptor activity. Involved in cellular response to lipopolysaccharide; regulation of sensory perception of pain; and wound healing. Located in cell surface. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); glomerulonephritis (multiple); hematologic Cancer (multiple); and immunodeficiency 20. Orthologous to several human genes including FCGR3A (Fc fragment of IgG receptor IIIa). [provided by Alliance of Genome Resources, Apr 2022]

Fcgr3a Products(1)

mRNA Protein Name
NM_207603.2 NP_997486.2 low affinity immunoglobulin gamma Fc region receptor III-A precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
19106808 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
19106808 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

low affinity immunoglobulin gamma Fc region receptor III-A

Fc fragment of IgG intermediate affinity IV receptor

Fc fragment of IgG receptor IIIa

Fc fragment of IgG, low affinity IIIa, receptor for (CD16)

Fc gamma receptor IIIa

IgG Fc receptor III-A

fcgammaRIV

transmembrane receptor FcgammaRIII-X

Recombinant Fcgr3a Proteins

Cat. No. Product Name Accession Purity
HY-P75621 Fc gamma RIIIA/CD16a Protein, Rat (HEK293, His, solution) XP_008767961.1 (L22-P200) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04831 FCGR3A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990710 Acimtamig / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fcgr3a NCBI NCBI:2214
Macaca fascicularis Fcgr3a NCBI NCBI:102140945